D
David F. Smith
Researcher at Cincinnati Children's Hospital Medical Center
Publications - 105
Citations - 4872
David F. Smith is an academic researcher from Cincinnati Children's Hospital Medical Center. The author has contributed to research in topics: Obstructive sleep apnea & Polysomnography. The author has an hindex of 27, co-authored 99 publications receiving 4040 citations. Previous affiliations of David F. Smith include Johns Hopkins University & University of Virginia.
Papers
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Journal ArticleDOI
Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E
Yuqing Huo,Andreas Schober,S. Bradley Forlow,David F. Smith,Matthew C. Hyman,Steffen Jung,Dan R. Littman,Christian Weber,Klaus Ley +8 more
TL;DR: The results indicate that circulating activated platelets and platelet–leukocyte/monocyte aggregates promote formation of atherosclerotic lesions.
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Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung
Jörg Reutershan,Margaret A. Morris,Tracy L. Burcin,David F. Smith,Daniel Chang,Mary S. Saprito,Klaus Ley +6 more
TL;DR: The data revealed what is believed to be a previously unrecognized role of endothelial and epithelial CXCR2 in LPS-induced PMN recruitment and lung injury.
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Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes
Cindy R. Sinars,Joyce Cheung-Flynn,Ronald A. Rimerman,Jonathan G. Scammell,David F. Smith,Jon Clardy +5 more
TL;DR: This structure of a multi-FKBP domain protein clarifies the arrangement of these domains and their possible interactions with other proteins, and reports here the x-ray structures of human and squirrel monkey FKBP51, to 2.7 Å.
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A pathway of multi-chaperone interactions common to diverse regulatory proteins: estrogen receptor, Fes tyrosine kinase, heat shock transcription factor Hsf1, and the aryl hydrocarbon receptor.
Satish C. Nair,Eric J. Toran,Ronald A. Rimerman,Scott J. Hjermstad,Thomas E. Smithgall,David F. Smith +5 more
TL;DR: Target proteins other than progesterone receptor were used in this cell-free system to assemble complexes in vitro and to compare the composition of resulting complexes, suggesting that each of these targets undergoes a common assembly pathway involving multiple chaperone components in addition to Hsp90.
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Human papillomavirus-related carcinomas of the sinonasal tract.
Justin A. Bishop,Theresa Guo,David F. Smith,Hao Wang,Takenori Ogawa,Sara I. Pai,William H. Westra +6 more
TL;DR: The presence of high-risk HPV in 21% of sinonasal carcinomas confirms HPV as an important oncologic agent of carcinomas arising in the sin onasal tract.