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David H. W. Steel
Researcher at Newcastle University
Publications - 272
Citations - 6302
David H. W. Steel is an academic researcher from Newcastle University. The author has contributed to research in topics: Medicine & Vitrectomy. The author has an hindex of 33, co-authored 225 publications receiving 4711 citations. Previous affiliations of David H. W. Steel include National Health Service & University of Sunderland.
Papers
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Journal ArticleDOI
An Active Contour Model for Segmenting and Measuring Retinal Vessels
TL;DR: This paper presents an algorithm for segmenting and measuring retinal vessels, by growing a ldquoRibbon of Twinsrdquo active contour model, which uses two pairs of contours to capture each vessel edge, while maintaining width consistency.
Journal ArticleDOI
Optic nerve head segmentation
TL;DR: The localization algorithm succeeded on all bar one usable image; the contour estimation algorithm was qualitatively assessed by an ophthalmologist as having Excellent-Fair performance in 83% of cases, and performs well even on blurred images.
Journal ArticleDOI
Measurement of retinal vessel widths from fundus images based on 2-D modeling
TL;DR: An algorithm to measure the vessel diameter to subpixel accuracy is presented, based on a two-dimensional difference of Gaussian model, which is optimized to fit aTwo-dimensional intensity vessel segment.
Journal ArticleDOI
Idiopathic vitreomacular traction and macular hole: a comprehensive review of pathophysiology, diagnosis, and treatment
TL;DR: Clinical studies have supported its use as an alternative to surgery in certain patient populations, however, further research is still needed with respect to greater understanding of the pathophysiology underlying the development of VMT and IMH.
Journal ArticleDOI
Efficient Stage-Specific Differentiation of Human Pluripotent Stem Cells Toward Retinal Photoreceptor Cells
TL;DR: The data highlight an important role for Dkk1 and Noggin in enhancing the differentiation of hESC and hiPSC toward retinal progenitor cells and photoreceptor precursors during the early stages of differentiation, while suggesting that further maturation of these cells into photoreceptors may not require additional factors and can ensue under minimal culture conditions.