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David J.A. Callen
Researcher at McMaster Children's Hospital
Publications - 21
Citations - 1387
David J.A. Callen is an academic researcher from McMaster Children's Hospital. The author has contributed to research in topics: Acute disseminated encephalomyelitis & Magnetic resonance imaging. The author has an hindex of 15, co-authored 21 publications receiving 1210 citations. Previous affiliations of David J.A. Callen include McMaster University & Women's College, Kolkata.
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Journal ArticleDOI
Beyond the hippocampus MRI volumetry confirms widespread limbic atrophy in AD
TL;DR: These results verify that system-wide limbic degeneration occurs in patients with AD, and atrophy in selected limbic structures was used to distinguish patients withAD from normal elderly individuals with over 90% accuracy in this select clinical sample.
Journal ArticleDOI
Role of MRI in the differentiation of ADEM from MS in children
David J.A. Callen,Manohar Shroff,Helen M. Branson,D. K. Li,Timothy Lotze,Derek Stephens,Brenda Banwell +6 more
TL;DR: MRI diagnostic criteria are proposed that may be useful in differentiating children experiencing the first attack of multiple sclerosis from those with monophasic acute disseminated encephalomyelitis.
Journal ArticleDOI
MRI parameters for prediction of multiple sclerosis diagnosis in children with acute CNS demyelination: a prospective national cohort study.
Leonard H. Verhey,Helen M. Branson,Manohar Shroff,David J.A. Callen,John G. Sled,Sridar Narayanan,A. Dessa Sadovnick,Amit Bar-Or,Douglas L. Arnold,Ruth Ann Marrie,Brenda Banwell +10 more
TL;DR: Specific MRI parameters can be used to predict diagnosis of MS in children with incident demyelination of the CNS and the ability to promptly identify children with MS will enhance timely access to care and will be important for future clinical trials in paediatric MS.
Journal ArticleDOI
MRI in the diagnosis of pediatric multiple sclerosis
David J.A. Callen,Manohar Shroff,Helen M. Branson,Timothy Lotze,D. K. Li,Derek Stephens,Brenda Banwell +6 more
TL;DR: Modifications to the currently established McDonald MRI criteria for lesion dissemination in space that will enhance the diagnostic accuracy of these criteria for multiple sclerosis in children are proposed.
Journal ArticleDOI
Mutations in KCNT1 cause a spectrum of focal epilepsies
Rikke S. Møller,Sarah E. Heron,Line H.G. Larsen,Chiao Xin Lim,Michael G. Ricos,Marta A. Bayly,Marjan J. A. van Kempen,Sylvia Klinkenberg,Ian Andrews,Ian Andrews,Kent Kelley,Gabriel M. Ronen,David J.A. Callen,Jacinta M McMahon,Simone C. Yendle,Gemma L. Carvill,Heather C Mefford,Rima Nabbout,Annapurna Poduri,Pasquale Striano,Maria Giuseppina Baglietto,Federico Zara,Nicholas J.C. Smith,Clair Pridmore,Elena Gardella,Marina Nikanorova,Hans Atli Dahl,Pia Gellert,Ingrid E. Scheffer,Boudewijn Gunning,Bente Kragh-Olsen,Leanne M. Dibbens +31 more
TL;DR: It is demonstrated that KCNT1 mutations are highly pleiotropic and are associated with phenotypes other than ADNFLE and MMFSI, and are now associated with Ohtahara syndrome, MMFSi, and nocturnal focal epilepsy.