T
Timothy Lotze
Researcher at Baylor College of Medicine
Publications - 117
Citations - 4921
Timothy Lotze is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Medicine & Multiple sclerosis. The author has an hindex of 30, co-authored 95 publications receiving 3765 citations. Previous affiliations of Timothy Lotze include Boston Children's Hospital.
Papers
More filters
Journal ArticleDOI
Recurrent reciprocal 1q21.1 deletions and duplications associated with microcephaly or macrocephaly and developmental and behavioral abnormalities
Nicola Brunetti-Pierri,Jonathan S. Berg,Fernando Scaglia,John W. Belmont,Carlos A. Bacino,Trilochan Sahoo,Seema R. Lalani,Brett H. Graham,Brendan Lee,Marwan Shinawi,Joseph J. Shen,Sung Hae L. Kang,Amber Pursley,Timothy Lotze,Gail L. Kennedy,Susan Lansky-Shafer,Christine Weaver,Elizabeth Roeder,Theresa A. Grebe,Georgianne L. Arnold,Terry Hutchison,Tyler Reimschisel,Stephen Amato,Michael T. Geragthy,Jeffrey W. Innis,Ewa Obersztyn,Beata Nowakowska,Sally Rosengren,Patricia I. Bader,Dorothy K. Grange,Sayed Naqvi,Adolfo D. Garnica,Saunder Bernes,Chin-To Fong,Anne M. Summers,W. David Walters,James R. Lupski,Pawel Stankiewicz,Sau Wai Cheung,Ankita Patel +39 more
TL;DR: It is proposed that recurrent reciprocal microdeletions and microduplications within 1q21.1 represent previously unknown genomic disorders characterized by abnormal head size along with a spectrum of developmental delay, neuropsychiatric abnormalities, dysmorphic features and congenital anomalies.
Journal ArticleDOI
Ataluren in patients with nonsense mutation Duchenne muscular dystrophy (ACT DMD): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
Craig M. McDonald,Craig Campbell,Ricardo Erazo Torricelli,Richard S. Finkel,Richard S. Finkel,Kevin M. Flanigan,Nathalie Goemans,Peter Heydemann,Anna Kamińska,Janbernd Kirschner,Francesco Muntoni,Andrés Nascimento Osorio,Ulrike Schara,Thomas Sejersen,Perry B. Shieh,H. Lee Sweeney,Haluk Topaloglu,Mar Tulinius,Juan J. Vílchez,Thomas Voit,Thomas Voit,Brenda Wong,Gary Elfring,H. Kroger,Xiaohui Luo,Joseph McIntosh,Tuyen Ong,Peter Riebling,Marcio Souza,R. Spiegel,Stuart W. Peltz,Eugenio Mercuri,Lindsay N. Alfano,Michelle Eagle,M. James,Linda Lowes,Anna Mayhew,Elena S. Mazzone,Leslie Nelson,Kristy Rose,Hoda Abdel-Hamid,Susan D. Apkon,Richard J. Barohn,Enrico Bertini,Clemens Bloetzer,Lausanne Canton de Vaud,Russell J. Butterfield,Brigitte Chabrol,Jong-Hee Chae,Daehak-ro Jongno-gu,Giacomi Pietro Comi,Basil T. Darras,Jahannaz Dastgir,Isabelle Desguerre,Raul G Escobar,Erika Finanger,Michela Guglieri,Imelda Hughes,Susan T. Iannaccone,Kristi J. Jones,Peter I. Karachunski,Martin Kudr,Timothy Lotze,Jean K. Mah,Katherine D. Mathews,Yoram Nevo,Julie A. Parsons,Yann Péréon,Alexandra Prufer de Queiroz Campos Araujo,J. Ben Renfroe,Maria Bernadete Dutra de Resende,Monique M. Ryan,Kathryn Selby,Gihan Tennekoon,Giuseppe Vita +74 more
TL;DR: Ataluren was generally well tolerated and most treatment-emergent adverse events were mild to moderate in severity, and there was a significant effect of ataluren in the prespecified subgroup of patients in the intention-to-treat population.
Journal ArticleDOI
CNS aquaporin-4 autoimmunity in children
Andrew McKeon,Vanda A. Lennon,Timothy Lotze,S. Tenenbaum,Jayne Ness,Mary Rensel,Nancy L. Kuntz,J. P. Fryer,Henry A. Homburger,Jill V. Hunter,Brian G. Weinshenker,Karl N. Krecke,Claudia F. Lucchinetti,Sean J. Pittock +13 more
TL;DR: The neurologic, serologic, and radiographic findings associated with CNS AQP4 autoimmunity in childhood are described, indicating a distinctive recurrent and widespread inflammatory CNS disease in children.
Journal ArticleDOI
Long-term effects of glucocorticoids on function, quality of life, and survival in patients with Duchenne muscular dystrophy: a prospective cohort study
Craig M. McDonald,Erik K Henricson,Richard T. Abresch,Tina Duong,Nanette C. Joyce,F. Hu,Paula R. Clemens,Eric P. Hoffman,Avital Cnaan,Heather Gordish-Dressman,Vijay Vishwanathan,S. Chidambaranathan,W. Douglas Biggar,Laura McAdam,Jean K. Mah,Mar Tulinius,Lauren P. Morgenroth,Robert T. Leshner,Carolina Tesi-Rocha,Mathula Thangarajh,Andrew J. Kornberg,Monique M. Ryan,Yoram Nevo,Alberto Dubrovsky,Hoda Abdel-Hamid,Anne M. Connolly,Alan Pestronk,Jean Teasley,Tulio E. Bertorin,Richard Webster,Hanna Kolski,Nancy L. Kuntz,Sherilyn W. Driscoll,John B. Bodensteiner,Jose Carlo,Ksenija Gorni,Timothy Lotze,John W. Day,Peter I. Karachunski +38 more
TL;DR: In patients with Duchenne muscular dystrophy, glucocorticoid treatment is associated with reduced risk of losing clinically meaningful mobility and upper limb disease progression milestones across the lifespan as well as reduced riskof death.
Journal ArticleDOI
Role of MRI in the differentiation of ADEM from MS in children
David J.A. Callen,Manohar Shroff,Helen M. Branson,D. K. Li,Timothy Lotze,Derek Stephens,Brenda Banwell +6 more
TL;DR: MRI diagnostic criteria are proposed that may be useful in differentiating children experiencing the first attack of multiple sclerosis from those with monophasic acute disseminated encephalomyelitis.