D
David Mendez
Researcher at European Bioinformatics Institute
Publications - 4
Citations - 2622
David Mendez is an academic researcher from European Bioinformatics Institute. The author has contributed to research in topics: chEMBL & Web service. The author has an hindex of 3, co-authored 4 publications receiving 1485 citations.
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Journal ArticleDOI
The ChEMBL database in 2017.
Anna Gaulton,Anne Hersey,Michal Nowotka,A. Patrícia Bento,Jon Chambers,David Mendez,Prudence Mutowo,Francis Atkinson,Louisa J. Bellis,Elena Cibrian-Uhalte,Mark Davies,Nathan Dedman,Anneli Karlsson,María Paula Magariños,John P. Overington,George Papadatos,Ines Smit,Andrew R. Leach +17 more
TL;DR: ChEMBL is an open large-scale bioactivity database that includes the annotation of assays and targets using ontologies, the inclusion of targets and indications for clinical candidates, addition of metabolic pathways for drugs and calculation of structural alerts.
Journal ArticleDOI
ChEMBL: towards direct deposition of bioassay data
David Mendez,Anna Gaulton,A. Patrícia Bento,Jon Chambers,Marleen De Veij,Eloy Felix,María Paula Magariños,Juan F Mosquera,Prudence Mutowo,Michal Nowotka,María Gordillo-Marañón,Fiona M. I. Hunter,Laura Junco,Grace Mugumbate,Milagros Rodríguez-López,Francis Atkinson,Nicolas Bosc,Chris J Radoux,Aldo Segura-Cabrera,Anne Hersey,Andrew R. Leach +20 more
TL;DR: Several important improvements have been made to ChEMBL in the last two years, including more robust capture and representation of assay details; a new data deposition system, allowing updating of data sets and deposition of supplementary data; and a completely redesigned web interface, with enhanced search and filtering capabilities.
Journal ArticleDOI
Using ChEMBL web services for building applications and data processing workflows relevant to drug discovery
TL;DR: This review highlights some of the audiences who may benefit from using the ChEMBL API, and the goals they can address, through the description of several use cases.
Journal ArticleDOI
MAIP: a web service for predicting blood-stage malaria inhibitors.
Nicolas Bosc,Eloy Felix,Ricardo Arcila,David Mendez,Martin R. Saunders,Darren V. S. Green,Jason Ochoada,Anang A. Shelat,Eric J. Martin,Preeti Iyer,Ola Engkvist,Andreas Verras,James Duffy,Jeremy N. Burrows,J. Mark. F. Gardner,Andrew R. Leach +15 more
TL;DR: The MAIP project as discussed by the authors is an open-source software platform for creating consensus in silico models that can be used to identify novel molecules that may have antimalarial properties.