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David R. Rubinow

Researcher at University of North Carolina at Chapel Hill

Publications -  375
Citations -  25515

David R. Rubinow is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Mood & Premenstrual dysphoric disorder. The author has an hindex of 82, co-authored 364 publications receiving 23457 citations. Previous affiliations of David R. Rubinow include National Institutes of Health & George Washington University.

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Journal ArticleDOI

Effects of gonadal steroids on reward circuitry function and anhedonia in women with a history of postpartum depression.

TL;DR: In this paper , the authors present data from a double-blinded pharmaco-fMRI study investigating the triggering of anhedonia and reward circuit activity in women, showing significant effects of reproductive hormones on rewardrelated brain function in women.
Journal ArticleDOI

Early Life Abuse Moderates the Effects of Intranasal Oxytocin on Symptoms of Premenstrual Dysphoric Disorder: Preliminary Evidence From a Placebo-Controlled Trial

TL;DR: This single-blind, placebo-controlled crossover trial examined the role of ELA in shaping the effects of intranasal OXT on daily behavioral symptoms in women with three or more prospectively-diagnosed cycling symptoms of premenstrual dysphoric disorder.
Journal ArticleDOI

Baseline anxiety-sensitivity to estradiol fluctuations predicts anxiety symptom response to transdermal estradiol treatment in perimenopausal women – A randomized clinical trial

TL;DR: In this paper , the authors investigated the relationship between E2 fluctuations, mood symptoms, and physiologic stress-reactivity (cortisol and interleukin-6) and whether differences in mood-sensitivity to E2 fluctuation predict mood responses to transdermal E2 treatment.
Book ChapterDOI

Gonadal Hormones and Behavior in Women: Concentrations versus Context

TL;DR: Evidence from neuroimaging and neuroendocrine studies in humans is described that demonstrate the important neuroregulatory effects of gonadal steroids on physiological systems mediating affective adaptation and sources of differential behavioral sensitivity in humans.