D
David R. Rubinow
Researcher at University of North Carolina at Chapel Hill
Publications - 375
Citations - 25515
David R. Rubinow is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Mood & Premenstrual dysphoric disorder. The author has an hindex of 82, co-authored 364 publications receiving 23457 citations. Previous affiliations of David R. Rubinow include National Institutes of Health & George Washington University.
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Journal ArticleDOI
Changes in plasma hormones across the menstrual cycle in patients with menstrually related mood disorder and in control subjects.
David R. Rubinow,M.Christine Hoban,D.Scott Galloway,Peter Roy-Byrne,Richard N. Andersen,George R. Merriam +5 more
TL;DR: The data suggest that premenstrual syndrome does not represent a simple hormonal deficiency and that the cited rationales for several of the proposed treatments are of questionable merit.
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Reduced anxiety and depression in cystic acne patients after successful treatment with oral isotretinoin
TL;DR: Significant reductions in anxiety were observed on several measures of anxiety after treatment, with mitigation of anxiety and depression most robust in those patients with the greatest dermatologic improvement with isotretinoin.
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Prospective Assessment of Menstrually Related Mood Disorders
TL;DR: In a preliminary application of this measure to 20 women with self-diagnosed premenstrual syndrome, eight had a mean depression rating during the week before menstruation that was 30% higher than During the week after cessation of menstruation.
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Radioimmunoassay of 3α-hydroxy-5α-pregnan-20-one in rat and human plasma
Robert H. Purdy,Perry H. Moore,P.Narasimha Rao,Nobuyoshi Hagino,Tatsumi Yamaguchi,Peter Schmidt,David R. Rubinow,A. Leslie Morrow,Steven M. Paul +8 more
TL;DR: A radioimmunoassay for measuring 3α-hydroxy-5α-pregnan-20-one in plasma has been developed and it was found that this centrally active progesterone metabolite was detected in plasma from female rats on the day ofestrus and in the plasma of women during the luteal phase of the menstrual cycle.
Journal ArticleDOI
Hormonal gain control of a medial preoptic area social reward circuit
Jenna A. McHenry,James M. Otis,Mark A. Rossi,J. Elliott Robinson,Oksana Kosyk,Noah W Miller,Zoe A. McElligott,Evgeny A. Budygin,Evgeny A. Budygin,Evgeny A. Budygin,David R. Rubinow,Garret D. Stuber +11 more
TL;DR: This work identifies a steroid-responsive subset of neurotensin-expressing mPOA neurons that interface with the ventral tegmental area (VTA) to form a socially engaged reward circuit and shows that mPOANts neurons preferentially encode attractive male cues compared to nonsocial appetitive stimuli.