Dawei Wang

TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.

TL;DR: A period of 7–13 days after illness onset is the critical stage in the COVID-19 course, which shows persistent lymphopenia, severe acute respiratory dyspnea syndrome, refractory shock, anuric acute kidney injury, coagulopathy, thrombocytopenia, and death.

TL;DR: Early initiation of corticosteroid use (≤ 3 days after ICU admission) was associated with an increased 90-day mortality and early use of methylprednisolone in the ICU is therefore not recommended in patients with severe COVID-19.

TL;DR: Ventilation support and hemodynamic support were the cornerstones for critical care and high viral load was associated with death of critically ill COVID-19 patients.

TL;DR: It is demonstrated that SARS-CoV-2 infection-related critical illness predominantly affected old individuals with comorbidities and characterized by severe hypoxemic respiratory failure, often requiring prolonged mechanical ventilation and rescue therapies.