Dean Brady

TL;DR: This study describes the design and synthesis of mimetic peptides modelled on the catalytic active site of the fructose-1,6-bisphosphate aldolase (FBPA) enzyme, which showed catalytic activity and the a Aldol products were obtained in low yields, but excellent enantioselectivity and moderate diastereoselectivities.

TL;DR: The acylation of the acetonitrile anion with lactones and esters in ethereal solvents was successfully exploited using inexpensive KOt-Bu to obtain a variety of β-ketonitriles and trifunctionalized building blocks, including useful O-unprotected diols.

TL;DR: This chapter contains sections titled: Industrial Production of Caffeic Acid-α-D-O-Glucoside Enzymatic Synthesis of 5-Methyluridine by Transglycosylation of Guanosine and Thymine Preparation and Use of Sucrose Phosphorylase as Cross-Linked Enzyme Aggregate.

TL;DR: In this article , a new approach for synthesizing triazole rings through the application of laccases, copper containing oxidoreductase enzymes, was outlined, and a series of benzothiazoles and benzimidazoles-functionalized alkynes were initially synthesized utilizing a biocatalysis laccase-based approach.

TL;DR: In this paper, a process for producing enzymes structures includes providing an emulsion of droplets of a first liquid phase dispersed in a second liquid phase, which is immiscible with the hydrophilic phase, and the enzyme molecules of the respective droplets are crosslinked so that individual enzyme structures, which are stable and in which the enzymes are immobilized with a majority of active sites of the enzymes being orientated either internally or externally, are formed from individual droplets.