D
Dean Ho
Researcher at National University of Singapore
Publications - 136
Citations - 10175
Dean Ho is an academic researcher from National University of Singapore. The author has contributed to research in topics: Drug delivery & Nanodiamond. The author has an hindex of 41, co-authored 128 publications receiving 8646 citations. Previous affiliations of Dean Ho include University of California & University of Maryland, Baltimore.
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Journal ArticleDOI
The properties and applications of nanodiamonds
TL;DR: The rational control of the mechanical, chemical, electronic and optical properties of nanodiamonds through surface doping, interior doping and the introduction of functional groups are discussed.
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Active Nanodiamond Hydrogels for Chemotherapeutic Delivery
TL;DR: Doxorubicin hydrochloride (DOX), an apoptosis-inducing drug widely used in chemotherapy, was successfully applied toward the functionalization of nanodiamond materials (NDs) and introduced toward murine macrophages as well as human colorectal carcinoma cells with preserved efficacy.
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Nanodiamond Therapeutic Delivery Agents Mediate Enhanced Chemoresistant Tumor Treatment
Edward Kai-Hua Chow,Xuan Zhang,Mark Chen,Robert Lam,Erik Robinson,Houjin Huang,Daniel J. Schaffer,Eiji Osawa,Andrei Goga,Dean Ho +9 more
TL;DR: Nanodiamond-based drug delivery significantly enhanced treatment efficacy and safety in multiple chemoresistant cancer models and ND-conjugated chemotherapy represents a promising, biocompatible strategy for overcoming chemoresistance and enhancing chemotherapy efficacy andSafety.
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Cancer Nanomedicine: From Drug Delivery to Imaging
Edward Kai-Hua Chow,Dean Ho +1 more
TL;DR: How particular materials lend themselves to specific applications, the progress to date in clinical translation of nanomedicine, and promising approaches that may catalyze clinical acceptance of nano are discussed.
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Polymer-Functionalized Nanodiamond Platforms as Vehicles for Gene Delivery
TL;DR: NDs are introduced as vectors for in vitro gene delivery via surface-immobilization with 800 Da polyethyleneimine (PEI800) and covalent conjugation with amine groups and serve as a rapid, scalable, and broadly applicable gene therapy strategy.