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Dean S. Carson

Researcher at Stanford University

Publications -  30
Citations -  2153

Dean S. Carson is an academic researcher from Stanford University. The author has contributed to research in topics: Oxytocin & Oxytocin receptor. The author has an hindex of 19, co-authored 28 publications receiving 1816 citations. Previous affiliations of Dean S. Carson include University of Sydney.

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A randomized controlled trial of intranasal oxytocin as an adjunct to exposure therapy for social anxiety disorder.

TL;DR: This study shows that the administration of oxytocin improves mental representations of self, following exposure therapy, and this effects may be either short term or situation specific.
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Intranasal oxytocin treatment for social deficits and biomarkers of response in children with autism

TL;DR: Findings indicate that OXT treatment enhances social abilities in children with ASD and that individuals with pretreatment OXT signaling deficits may stand to benefit the most from Oxt treatment.
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Plasma oxytocin concentrations and OXTR polymorphisms predict social impairments in children with and without autism spectrum disorder.

TL;DR: Evidence is provided that blood OXT concentrations are highly heritable within families, yet also strongly predict social functioning in ASD children, their unaffected siblings, and healthy control children, and these findings also extend to OXT receptor genotypes which are significantly associated with differences in social functioning independent of disease status.
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Cerebrospinal fluid and plasma oxytocin concentrations are positively correlated and negatively predict anxiety in children

TL;DR: This study provides the first empirical support for the use of blood measures of OXT as a surrogate for central OXT activity, validated in the context of behavioral functioning, and suggests that impaired OXT signaling may be a biomarker of anxiety in humans, and a potential target for therapeutic development in individuals with anxiety disorders.
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Oxytocin decreases methamphetamine self-administration, methamphetamine hyperactivity, and relapse to methamphetamine-seeking behaviour in rats.

TL;DR: Oxytocin may have a powerful inhibitory effect on the motivation to consume methamphetamine and on hyperactivity associated with acute methamphetamine intoxication, point to the potential utility of human trials of oxytocin as a therapeutic treatment for methamphetamine addiction.