D
Debra T. Silverman
Researcher at National Institutes of Health
Publications - 373
Citations - 25928
Debra T. Silverman is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Population & Bladder cancer. The author has an hindex of 82, co-authored 338 publications receiving 23066 citations. Previous affiliations of Debra T. Silverman include Government of the United States of America & International Agency for Research on Cancer.
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Journal ArticleDOI
Selection of Controls in Case-Control Studies I. Principles
TL;DR: In this paper, a theoretical framework for selecting controls in case-control studies is developed and three principles of comparability are described, which can reduce selection, confounding, and information bias.
Journal ArticleDOI
Association between smoking and risk of bladder cancer among men and women
Neal D. Freedman,Debra T. Silverman,Albert R. Hollenbeck,Arthur Schatzkin,Christian C. Abnet +4 more
TL;DR: Compared with a pooled estimate of US data from cohorts initiated between 1963 and 1987, relative risks for smoking in the more recent NIH-AARP Diet and Health Study cohort were higher, with PARs for women comparable with those for men.
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Selection of Controls in Case-Control Studies: II. Types of Controls
TL;DR: Types of control groups are evaluated and advantages and disadvantages of population controls, neighborhood controls, hospital or registry controls, medical practice controls, friend controls, and relative controls are considered.
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NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses.
Montserrat Garcia-Closas,Núria Malats,Debra T. Silverman,Mustafa Dosemeci,Manolis Kogevinas,David W. Hein,Adonina Tardón,Consol Serra,Alfredo Carrato,Reina García-Closas,Josep Lloreta,Gemma Castaño-Vinyals,Meredith Yeager,Robert Welch,Stephen J. Chanock,Nilanjan Chatterjee,Sholom Wacholder,Claudine Samanic,Montserrat Torà,Francisco J. Martín Fernández,Francisco X. Real,Nathaniel Rothman +21 more
TL;DR: The GSTM1 null genotypes increases the overall risk of bladder cancer, and the NAT2 slow-acetylator genotype increases risk particularly among cigarette smokers, providing compelling evidence for the role of common polymorphisms in the aetiology of cancer.
Journal ArticleDOI
Bladder Cancer and Exposure to Water Disinfection By-Products through Ingestion, Bathing, Showering, and Swimming in Pools
Cristina M. Villanueva,Kenneth P. Cantor,Joan O. Grimalt,Núria Malats,Debra T. Silverman,Adonina Tardón,Reina García-Closas,Consol Serra,Alfredo Carrato,Gemma Castaño-Vinyals,Ricard Marcos,Nathaniel Rothman,Francisco X. Real,Mustafa Dosemeci,Manolis Kogevinas +14 more
TL;DR: Long-term THM exposure was associated with a twofold bladder cancer risk, with an odds ratio of 2.10 (95% confidence interval: 1.09, 4.02) for average household THM levels of >49 versus < or =8 micro g/liter.