L
Lei Ren
Researcher at Xiamen University
Publications - 187
Citations - 5655
Lei Ren is an academic researcher from Xiamen University. The author has contributed to research in topics: Medicine & Engineering. The author has an hindex of 36, co-authored 134 publications receiving 3967 citations. Previous affiliations of Lei Ren include Peking Union Medical College & National University of Singapore.
Papers
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Journal ArticleDOI
Targeting Negative Surface Charges of Cancer Cells by Multifunctional Nanoprobes.
Bingdi Chen,Wenjun Le,Yilong Wang,Zhuoquan Li,Dong Wang,Lei Ren,Ling Lin,Shaobin Cui,Jennifer J. Hu,Yihui Hu,Pengyuan Yang,Rodney C. Ewing,Donglu Shi,Zheng Cui +13 more
TL;DR: The metabolically active cancer cells are shown to a unique surface electrostatic pattern that can be used for recovering cancer cells from the circulating blood and other solutions.
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Sequentially Responsive Therapeutic Peptide Assembling Nanoparticles for Dual-Targeted Cancer Immunotherapy.
Keman Cheng,Keman Cheng,Yanping Ding,Yanping Ding,Ying Zhao,Ying Zhao,Shefang Ye,Xiao Zhao,Yinlong Zhang,Tianjiao Ji,Huanhuan Wu,Bin Wang,Bin Wang,Gregory J. Anderson,Lei Ren,Guangjun Nie,Guangjun Nie +16 more
TL;DR: Together, this study offers new opportunities for dual-targeted cancer immunotherapy through functional peptide assembling nanoparticles with design features that are sequentially responsive to the multiple hallmarks of the tumor microenvironment.
Journal ArticleDOI
Novel approach to fabricate porous gelatin-siloxane hybrids for bone tissue engineering.
TL;DR: Porous and bioactive gelatin-siloxane hybrids were successfully synthesized by using a combined sol-gel processing, post-gelation soaking, and freeze-drying process to provide a novel kind of materials in the developments and optimization of bone tissue engineering.
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Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles.
TL;DR: It is indicated that polysorbate-80 coated PBCA nanoparticles could be a feasible carrier for temozolomide delivery to the brain and may improve on targeted therapy for malignant brain tumors in the future.
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One-step synthesis of monodisperse, water-soluble ultra-small Fe3O4 nanoparticles for potential bio-application
Lihua Shen,Jian-feng Bao,Dong Wang,Yixiao Wang,Zhiwei Chen,Lei Ren,Xi Zhou,Xue-bin Ke,Min Chen,An-qi Yang +9 more
TL;DR: It is reported that ultra-small, monodisperse, water-dispersible magnetite (Fe(3)O(4)) nanoparticles can be synthesized by a facile one-pot approach using trisodium citrate as crystal grain growth inhibitor and stabilizer in polyol solution and exhibit an excellent long-term colloidal stability.