D
Démi van Gent
Researcher at Vanderbilt University Medical Center
Publications - 2
Citations - 109
Démi van Gent is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Cohesin & Acetylation. The author has an hindex of 1, co-authored 1 publications receiving 50 citations.
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Astrocyte and Oligodendrocyte Cross-Talk in the Central Nervous System.
TL;DR: Emerging evidence of astrocyte-oligodendrocytes communication in health and disease is reviewed to reveal important insights into the pathogenesis and treatment of CNS diseases.
Journal ArticleDOI
The cohesin acetylation cycle controls chromatin loop length through a PDS5A brake mechanism
Marjon S. van Ruiten,Démi van Gent,Ángela Sedeño Cacciatore,Astrid Fauster,Laureen Willems,Maarten L. Hekkelman,Liesbeth Hoekman,Maarten Altelaar,Judith H.I. Haarhuis,Thijn R. Brummelkamp,Elzo de Wit,Benjamin D. Rowland +11 more
TL;DR: In this paper , the authors show that the cohesin acetylation cycle controls the three-dimensional genome in human cells, and that the interaction of cohesins with PDS5A acts as a brake that enables the pausing and restart of loop enlargement.