D
Denise Kaden
Researcher at Dresden University of Technology
Publications - 9
Citations - 206
Denise Kaden is an academic researcher from Dresden University of Technology. The author has contributed to research in topics: Adrenal gland & Metanephrine. The author has an hindex of 3, co-authored 9 publications receiving 130 citations.
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Journal ArticleDOI
Reference intervals for plasma concentrations of adrenal steroids measured by LC-MS/MS: Impact of gender, age, oral contraceptives, body mass index and blood pressure status.
Graeme Eisenhofer,Mirko Peitzsch,Denise Kaden,Katharina Langton,Christina Pamporaki,Jimmy Masjkur,George Tsatsaronis,Anastasios Mangelis,Tracy Ann Williams,Martin Reincke,Jacques W.M. Lenders,Stefan R. Bornstein +11 more
TL;DR: Age and gender are the most important variables for plasma steroid reference intervals, which have been established here according to those variables for a panel of 16 steroids primarily useful for diagnosis and subtyping of patients with endocrine hypertension.
Journal ArticleDOI
Reference intervals for LC-MS/MS measurements of plasma free, urinary free and urinary acid-hydrolyzed deconjugated normetanephrine, metanephrine and methoxytyramine.
Graeme Eisenhofer,Mirko Peitzsch,Denise Kaden,Katharina Langton,Anastasios Mangelis,Christina Pamporaki,Jimmy Masjkur,Aikaterini Geroula,Max Kurlbaum,Timo Deutschbein,Felix Beuschlein,Felix Beuschlein,Aleksander Prejbisz,Stefan R. Bornstein,Jacques W.M. Lenders,Jacques W.M. Lenders +15 more
TL;DR: Impacts of demographic and anthropometric variables on catecholamine metabolites are clarified, use of age-specific reference intervals for plasma normetanephrine is verified and sex most practical for urinary metabolites is established.
Journal ArticleDOI
Plasma Steroid Profiles in Subclinical Compared With Overt Adrenal Cushing Syndrome
Jimmy Masjkur,Matthias Gruber,Mirko Peitzsch,Denise Kaden,Guido Di Dalmazi,Guido Di Dalmazi,Martin Bidlingmaier,Stephanie Zopp,Katharina Langton,Julia Fazel,Felix Beuschlein,Stefan R. Bornstein,Martin Reincke,Graeme Eisenhofer +13 more
TL;DR: Distinct plasma steroid profiles in patients with SC may provide a simple and reliable screening method for establishing the diagnosis of subclinical Cushing's syndrome.
Journal ArticleDOI
Harmonization of LC-MS/MS Measurements of Plasma Free Normetanephrine, Metanephrine, and 3-Methoxytyramine.
Mirko Peitzsch,Talia Novos,Denise Kaden,Max Kurlbaum,Antonius E. van Herwaarden,Daniel Müller,Jo Adaway,Eric Grouzmann,Brett C. McWhinney,Kirsten Hoad,Gerald A Woollard,Ido P. Kema,Christopher Boot,Martin Fassnacht,Fred C.G.J. Sweep,Tze Ping Loh,Andrea R. Horvath,Graeme Eisenhofer +17 more
TL;DR: In this article, the authors evaluated the status of harmonization of liquid chromatography-tandem mass spectrometry-based measurements of plasma metanephrines and methoxytyramine and clinical interpretation of test results.
Journal ArticleDOI
HIF1α is a direct regulator of steroidogenesis in the adrenal gland.
Deepika Watts,Johanna Stein,Ana Meneses,Nicole Bechmann,Ales Neuwirth,Denise Kaden,Anja Krüger,Anupam Sinha,Vasileia Ismini Alexaki,Luis G. Perez-Rivas,Stefan Kircher,Antoine Martinez,Marily Theodoropoulou,Graeme Eisenhofer,Mirko Peitzsch,Ali El-Armouche,Triantafyllos Chavakis,Ben Wielockx +17 more
TL;DR: In this paper, the authors reveal a prominent role for HIF1α in the synthesis of virtually all steroids in vivo, and propose that HIF 1α is a vital regulator of steroidogenesis as its modulation in adrenocortical cells dramatically impacts hormone synthesis.