D
Dennis E. Hallahan
Researcher at Washington University in St. Louis
Publications - 270
Citations - 12479
Dennis E. Hallahan is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Cancer & Radiation therapy. The author has an hindex of 61, co-authored 264 publications receiving 11490 citations. Previous affiliations of Dennis E. Hallahan include Harvard University & University of Washington.
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Journal ArticleDOI
Imaging mass spectrometry: a new technology for the analysis of protein expression in mammalian tissues.
TL;DR: Imaging MS joins techniques such as immunochemistry and fluorescence microscopy for the study of the spatial arrangement of molecules within biological tissues for the unraveling and understanding the molecular complexities of cells.
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Noninvasive Cardiac Radiation for Ablation of Ventricular Tachycardia
Phillip S. Cuculich,Matthew R. Schill,Rojano Kashani,Sasa Mutic,Adam Lang,Daniel H. Cooper,Mitchell N. Faddis,Marye J. Gleva,Amit Noheria,Timothy W. Smith,Dennis E. Hallahan,Yoram Rudy,Clifford G. Robinson +12 more
TL;DR: In five patients with refractory ventricular tachycardia, noninvasive treatment with electrophysiology‐guided cardiac radioablation markedly reduced the burden of ventricular gyrations.
Journal Article
Inhibition of Vascular Endothelial Growth Factor Receptor Signaling Leads to Reversal of Tumor Resistance to Radiotherapy
Ling Geng,Edwin F. Donnelly,Gerald McMahon,Lin Pc,Sierra-Rivera E,Oshinka H,Dennis E. Hallahan +6 more
TL;DR: It is demonstrated that the tumor microenvironment including the survival of tumor-associated endothelial cells contributes to tumor blood vessel resistance to therapy.
Journal Article
SU11248 Maintenance Therapy Prevents Tumor Regrowth after Fractionated Irradiation of Murine Tumor Models
Aaron J. Schueneman,Eric Himmelfarb,Ling Geng,Jiahua Tan,Edwin F. Donnelly,Dirk B. Mendel,Gerald McMahon,Dennis E. Hallahan +7 more
TL;DR: SU11248 enhances radiation-induced endothelial cytotoxicity, resulting in tumor vascular destruction and tumor control when combined with fractionated radiotherapy in murine tumor models, and inhibition of angiogenesis well beyond radiation therapy may be a promising treatment paradigm for refractory human neoplasms.
Journal ArticleDOI
Phase I/II Trial of Electrophysiology-Guided Noninvasive Cardiac Radioablation for Ventricular Tachycardia.
Clifford G. Robinson,Pamela Samson,K.M.S. Moore,Geoffrey D. Hugo,Nels C. Knutson,Sasa Mutic,S. Murty Goddu,Adam Lang,Daniel H. Cooper,Mitchell N. Faddis,Amit Noheria,Timothy W. Smith,Pamela K. Woodard,Robert J. Gropler,Dennis E. Hallahan,Yoram Rudy,Phillip S. Cuculich +16 more
TL;DR: Noninvasive electrophysiology-guided cardiac radioablation is associated with markedly reduced ventricular arrhythmia burden with modest short-term risks, reduction in antiarrhythmic drug use, and improvement in quality of life.