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Dexter D’Sa
Researcher at University of Sydney
Publications - 10
Citations - 84
Dexter D’Sa is an academic researcher from University of Sydney. The author has contributed to research in topics: Particle & Elasticity (economics). The author has an hindex of 6, co-authored 10 publications receiving 71 citations. Previous affiliations of Dexter D’Sa include University of California, Berkeley & AstraZeneca.
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Journal ArticleDOI
Multi-Solvent Microdroplet Evaporation: Modeling and Measurement of Spray-Drying Kinetics with Inhalable Pharmaceutics
Mani Ordoubadi,Florence K. A. Gregson,Omar Melhem,David Barona,Rachael E. H. Miles,Dexter D’Sa,Sandra Gracin,David Lechuga-Ballesteros,Jonathan P. Reid,Warren H. Finlay,Reinhard Vehring +10 more
TL;DR: Numerical and experimental analysis of multi-solvent systems indicate that spray-drying near the iso-compositional ratio simplifies the design and process development of such systems.
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NanoXCT: A Novel Technique to Probe the Internal Architecture of Pharmaceutical Particles
TL;DR: This study reports the first series of non-destructive 3D visualizations of inhalable pharmaceutical particles and presents a powerful tool to dissect and observe the interior of pharmaceutical particles, including those of a respirable size.
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Attachment of micro- and nano-particles on tipless cantilevers for colloidal probe microscopy.
TL;DR: Nano-colloidal probes were used to conduct topographical, instantaneous force, and adhesive force mapping measurements in dry and liquid media conveying their versatility and functionality in studying nano- Colloidal probe systems.
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High-throughput indentational elasticity measurements of hydrogel extracellular matrix substrates
Dexter D’Sa,Elena M. de Juan Pardo,Elena M. de Juan Pardo,Rosalia de las Rivas Astiz,Rosalia de las Rivas Astiz,Shamik Sen,Sanjay Kumar +6 more
TL;DR: A rapid method based on indentation of the substrate with a ferromagnetic sphere and optical tracking of the resulting deformation yields order-of-magnitude agreement with atomic force microscopy elasticity measurements, but that the degree of this agreement depends strongly on sphere density and gel elasticity.
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Predicting physical stability in pressurized metered dose inhalers via dwell and instantaneous force colloidal probe microscopy.
TL;DR: Two novel dwell force techniques were employed to mimic long-term particle interactions present in pMDIs, using particles of various internal structures and a model liquid propellant as a model system to evaluate the applicability of CPM to predict actual pMDI physical stability.