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Dezhi Mu

Researcher at Sichuan University

Publications -  300
Citations -  7665

Dezhi Mu is an academic researcher from Sichuan University. The author has contributed to research in topics: Medicine & Neuroprotection. The author has an hindex of 39, co-authored 269 publications receiving 6130 citations. Previous affiliations of Dezhi Mu include University of California, San Francisco & Boston Children's Hospital.

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The integrin αvβ8 mediates epithelial homeostasis through MT1-MMP–dependent activation of TGF-β1

TL;DR: It is shown that SLC binds to αvβ8, an integrin expressed by normal epithelial and neuronal cells in vivo, which results in the membrane type 1 (MT1)-MMP–dependent release of active TGF-β, which leads to autocrine and paracrine effects on cell growth and matrix production.
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Apnea of prematurity: from cause to treatment

TL;DR: The physiology and pathophysiology behind AOP are discussed, including the laryngeal chemoreflex and sensitivity to inhibitory neurotransmitters, as are the mechanisms by which different therapies may work and the potential long-term neurodevelopmental consequences of AOP and its treatment.
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Erythropoietin enhances long-term neuroprotection and neurogenesis in neonatal stroke.

TL;DR: The results suggest that EPO may neuroprotect and direct cell fate toward neurogenesis and away from gliogenesis in neonatal stroke.
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Erythropoietin improves functional and histological outcome in neonatal stroke.

TL;DR: EPO treatment markedly preserved hemispheric volume and decreased the expansion of SVZ unilaterally and significantly improved the asymmetry of forelimb use following neonatal stroke, suggesting EPO may be a candidate in the treatment of Neonatal stroke.