D
Dhanapal Sakthisekaran
Researcher at University of Madras
Publications - 90
Citations - 4143
Dhanapal Sakthisekaran is an academic researcher from University of Madras. The author has contributed to research in topics: Benzo(a)pyrene & Lipid peroxidation. The author has an hindex of 34, co-authored 89 publications receiving 3649 citations.
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Journal ArticleDOI
The Vascular Endothelium and Human Diseases
Peramaiyan Rajendran,Thamaraiselvan Rengarajan,Jayakumar Thangavel,Yutaka Nishigaki,Dhanapal Sakthisekaran,Gautam Sethi,Ikuo Nishigaki +6 more
TL;DR: In this review the main endothelial abnormalities found in various human diseases such as cancer, diabetes mellitus, atherosclerosis, and viral infections are addressed.
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Protective role of Apigenin on the status of lipid peroxidation and antioxidant defense against hepatocarcinogenesis in Wistar albino rats.
J Prince Vijeya Singh,Karuppaiyah Selvendiran,S. Mumtaz Banu,Radhakrishnan Padmavathi,Dhanapal Sakthisekaran +4 more
TL;DR: It is concluded that apigenin prevents LPO and protects antioxidant system in DEN induced and phenobarbital promoted hepatocellular carcinogenesis and protects oxidative stress caused by the carcinogen.
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Role of human organic anion transporter 4 in the transport of ochratoxin A.
Ellappan Babu,Michio Takeda,Shinichi Narikawa,Yukari Kobayashi,Atsushi Enomoto,Akihiro Tojo,Seok Ho Cha,Takashi Sekine,Dhanapal Sakthisekaran,Hitoshi Endou +9 more
TL;DR: Results indicate that hOAT4 mediates the high-affinity transport of ochratoxin A on the apical side of the proximal tubule, whereas the transport characteristics of OTA are distinct from those by basolateral OATs.
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Cytoprotective effect of piperine against benzo[a]pyrene induced lung cancer with reference to lipid peroxidation and antioxidant system in Swiss albino mice.
TL;DR: The data suggest that piperine may extend its chemopreventive effect by modulating lipid peroxidation and augmenting antioxidant defense system.
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Antitumour activity of crocetin in accordance to tumor incidence, antioxidant status, drug metabolizing enzymes and histopathological studies.
Venkatraman Magesh,Jayapal Prince Vijaya Singh,Karupaya Selvendiran,Ganapathy Ekambaram,Dhanapal Sakthisekaran +4 more
TL;DR: Crocetin proves to scavenge free radical and plays an important role in cellular function and Tumor incidence and histopathological studies proves crocetin is a potent antitumour agent.