D
Dharamainder Choudhary
Researcher at University of Connecticut Health Center
Publications - 31
Citations - 1393
Dharamainder Choudhary is an academic researcher from University of Connecticut Health Center. The author has contributed to research in topics: DNA & Oligonucleotide. The author has an hindex of 17, co-authored 31 publications receiving 1262 citations. Previous affiliations of Dharamainder Choudhary include University of Connecticut.
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Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues.
TL;DR: The present study compared the relative expression pattern of 10 orthologous CYP forms from families 1-4 in cDNA panels of human and mouse fetal and adult tissues to suggest possible involvement in development.
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Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues.
TL;DR: Tissue-specific P450-expression profiles reported in this study provide a reference for more focused analysis of the tissue-specific and developmental functions of the cytochrome P450 monooxygenases.
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Metabolism of retinoids and arachidonic acid by human and mouse cytochrome p450 1b1
TL;DR: A comparison of the kinetics of this metabolism by mouse and human CYP1B1 orthologs revealed the mouse enzyme to have a more favorable metabolism of DMBA, with a catalytic efficiency ratio (CER) of 0.23.
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Antioxidant and non-toxic properties of Piper betle leaf extract: in vitro and in vivo studies
TL;DR: The antioxidant activity of P. betle leaf extract is indicated and its potential to elevate the antioxidant status in the animals is indicated.
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The Role of Pyruvate Dehydrogenase Kinase-4 (PDK4) in Bladder Cancer and Chemoresistance
Benjamin L. Woolbright,Dharamainder Choudhary,Andrew Mikhalyuk,Cassandra J Trammel,Sambantham Shanmugam,Erika Abbott,Carol C. Pilbeam,John A. Taylor +7 more
TL;DR: Findings indicate inhibition of PDK4 may potentiate cisplatin-induced cell death and warrant further studies investigating the mechanism through which this occurs.