D
Dharmendra Singh
Researcher at Ipca Laboratories Ltd.
Publications - 39
Citations - 411
Dharmendra Singh is an academic researcher from Ipca Laboratories Ltd.. The author has contributed to research in topics: Antimicrobial & Mass spectrometry. The author has an hindex of 12, co-authored 39 publications receiving 338 citations.
Papers
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Journal ArticleDOI
Identification and characterization of process related impurities in chloroquine and hydroxychloroquine by LC/IT/MS, LC/TOF/MS and NMR.
Vaijanath G. Dongre,Pradeep D. Ghugare,Pravin P. Karmuse,Dharmendra Singh,Atul N. Jadhav,Ashok Kumar +5 more
TL;DR: The focus of this study is identification and characterization of major unknown impurities in chloroquine (CQ) and hydroxychloroquine bulk drug samples using liquid chromatography/ion trap mass spectrometry (LC/IT/MS) and liquid Chromatography/time of flight mass spectrumetry ( LC/TOF/MS).
Patent
A one-pot process for the preparation of antiemetic agent, 1,2,3,9-tetrahydro-9-methyl-3[(2-methyl)-1h-imidazole-1-yl)methyl]-4h-carbazol-4-o
Ashok Kumar,Dharmendra Singh,Atul N. Jadhav,Navinchandra Darpan Pandya,Shankar Deepak Panmand,Ramsingh Gajendrasingh Thakur +5 more
TL;DR: In this article, a one-pot industrial process for preparing 1,2,3,9-tetrahydro-9-methyl-3-[(methyl-1H-imidazole-1-yl)methyl]-4H-carbazol-4-one of Formula-(I) was described.
Journal ArticleDOI
Solid state investigation and characterization of the polymorphic and pseudopolymorphic forms of indapamide.
Pradeep D. Ghugare,Pradeep D. Ghugare,Pradeep D. Ghugare,Vaijanath G. Dongre,Pravin P. Karmuse,Pravin P. Karmuse,Ragnesh Kumar Rana,Dharmendra Singh,Ashok Kumar,Zoeb A. Filmwala +9 more
TL;DR: Systematic analysis confirmed the existence of a polymorphic and three pseudopolymorphic forms of indapamide, a diuretic drug generally used for the treatment of hypertension, and methods of preparation of the polymorphs and pseudopoly Morphs are described.
Journal ArticleDOI
Synthesis and antimicrobial evaluation of 1,4-disubstituted 1,2,3-triazoles with aromatic ester functionality
TL;DR: Some of the synthesized 1,4-disubstituted 1,2,3-triazoles possess comparable or even better antibacterial, antitubercular and antifungal activities than reference drugs against tested bacterial, mycobacterial and fungal strains, respectively.
Journal ArticleDOI
Efficient Method for Demethylation of Aryl Methyl Ether Using Aliquat-336
TL;DR: In this paper, a rapid method for selective cleavage of aryl methylethers can be achieved in the presence of a protic acid and a catalytic amount of phase transfer catalyst (Aliquat-336).