D
Dhruva Bhattacharya
Researcher at University of Arizona
Publications - 20
Citations - 2044
Dhruva Bhattacharya is an academic researcher from University of Arizona. The author has contributed to research in topics: Autophagy & Entamoeba histolytica. The author has an hindex of 15, co-authored 20 publications receiving 1780 citations. Previous affiliations of Dhruva Bhattacharya include University of New Mexico & Stanford University.
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Journal ArticleDOI
Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β
Nicolas Dupont,Shanya Jiang,Manohar Pilli,Wojciech Ornatowski,Dhruva Bhattacharya,Vojo Deretic +5 more
TL;DR: This work shows that in mammalian cells, autophagy has a hitherto unappreciated positive contribution to the biogenesis and secretion of the proinflammatory cytokine IL‐1β via an export pathway that depends on Atg5, inflammasome, at least one of the two mammalian Golgi reassembly stacking protein (GRASP) paralogues, GRASP55 (GORASP2) and Rab8a.
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Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation
Eliseo F. Castillo,Alexander Dekonenko,John Arko-Mensah,Michael A. Mandell,Nicolas Dupont,Shanya Jiang,Monica Delgado-Vargas,Graham S. Timmins,Dhruva Bhattacharya,Hongliang Yang,Julie A. Hutt,C. Rick Lyons,Karen M. Dobos,Vojo Deretic +13 more
TL;DR: It is shown that autophagy plays a dual role against tuberculosis: antibacterial and anti-inflammatory, suppressing both M. tuberculosis growth and damaging inflammation.
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Regulatory Coordination between Two Major Intracellular Homeostatic Systems HEAT SHOCK RESPONSE AND AUTOPHAGY
Karol Dokladny,Micah Zuhl,Michael A. Mandell,Dhruva Bhattacharya,Suzanne M. Schneider,Vojo Deretic,Pope L. Moseley +6 more
TL;DR: It is found for the first time that heat shock response controls autophagy thus connecting and coordinating the two extreme ends of the homeostatic systems in the eukaryotic cell.
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Evaluation of Genetic Diversity among Pseudomonas citronellolis Strains Isolated from Oily Sludge-Contaminated Sites
TL;DR: Results indicate that a combination of Rep-PCR fingerprinting and PCR-based ribotyping can be used as a high-resolution genomic fingerprinting method for elucidating intraspecies diversity among strains of P. citronellolis.
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Degradation of Polycyclic Aromatic Hydrocarbons by a Newly Discovered Enteric Bacterium, Leclercia adecarboxylata
TL;DR: A bacterial strain capable of degrading polycyclic aromatic hydrocarbons for use as the sole carbon source was isolated from oily-sludge-contaminated soil and showed 98.8% homology to that of Leclercia adecarboxylata.