Diederica D. Claeys

TL;DR: Thorough experimental analysis of cross-linking reactions in a series of contexts, combined with theoretical calculations, permit structural characterization of the formed species and allow assessment of the origin of the enhanced cross-link selectivity.

TL;DR: In this article, a ring-closing ring-opening sequence was used for the synthesis of bicyclic hydantoin derivatives, starting from pyroglutamates and then starting from highly substituted hydantoins under very mild conditions.

TL;DR: This article presents a Kennard-Stone-based algorithm, with a distance measure based on the distance matrix, for the selection of the most diverse set of conformations, successfully applied to macrocyclic alkenes.

TL;DR: This work wanted to investigate possible routes via ring opening of alpha-amino phosphonates with an oxanorbornene skeleton, as these can be synthesized with high stereoselectivity using different Lewis acids, leading to a range of products.

TL;DR: In this paper, a molecular modeling approach was developed to predict proton chemical shifts in sufficient agreement with experimental NMR measurements to guide structure elucidation, which was applied on the Drew-Dickerson d(CGCGAATTCGCG)2 dodecamer as a benchmark system and the mispair-aligned N3T-ethyl-N3T cross-linked d(CGAAAT*TTTCG) 2 undecamer.