Diego Gallo

TL;DR: It is concluded that the plausibility of the assumption of idealized velocity profiles as inlet BCs in personalized computational models can lead to misleading representations of the aortic hemodynamics both in terms of disturbed shear and bulk flow structures.

TL;DR: The in vivo quantification of the bulk flow features emerging in this study would offer a practical way to infer the presence of disturbed shear in large-scale in vivo studies of local risk factors in atherosclerosis.

TL;DR: In subject-specific computational hemodynamics models of the human aorta the imposition of BC settings based on non-invasively measured flow rate waveforms influences indicators of abnormal flow to a large extent and a BCs set-up assuring realistic, subject- specific instantaneous flow rate distribution must be applied when BCs such as flow rates are prescribed.

TL;DR: This study demonstrates the feasibility to virtually investigate the haemodynamics of patient-specific coronary bifurcation geometries through CFD of realistic stented coronary artery models which replicate the complete clinical procedure of stent implantation.

TL;DR: The findings underscore that the overall effect of the assumptions done in order to simulate blood flow within the carotid bifurcation is mainly in the hot-spot modulation of the hemodynamic descriptors of atherosusceptible areas, rather than in their distribution.