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Umberto Morbiducci
Researcher at Polytechnic University of Turin
Publications - 247
Citations - 5906
Umberto Morbiducci is an academic researcher from Polytechnic University of Turin. The author has contributed to research in topics: Acute coronary syndrome & Medicine. The author has an hindex of 36, co-authored 227 publications receiving 4753 citations. Previous affiliations of Umberto Morbiducci include Sapienza University of Rome & University of Alberta.
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Journal ArticleDOI
In Vivo Quantification of Helical Blood Flow in Human Aorta by Time-Resolved Three-Dimensional Cine Phase Contrast Magnetic Resonance Imaging
Umberto Morbiducci,Raffaele Ponzini,Giovanna Rizzo,Marcello Cadioli,Antonio Esposito,Francesco De Cobelli,Alessandro Del Maschio,Franco Maria Montevecchi,Alberto Redaelli +8 more
TL;DR: This study shows that the quantification of helical blood flow in vivo is feasible, and it might allow detection of anomalies in the expected physiological development of helicals flow in aorta and accordingly, could be used in a diagnostic/prognostic index for clinical practice.
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Platelet activation due to hemodynamic shear stresses: damage accumulation model and comparison to in vitro measurements.
TL;DR: A phenomenological model for platelet cumulative damage, identified by means of genetic algorithms (GAs) was correlated with in vitro experiments conducted in a Hemodynamic Shearing Device (HSD), and model predictions were in very good agreement with the experimental results.
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Mechanistic insight into the physiological relevance of helical blood flow in the human aorta: an in vivo study
Umberto Morbiducci,Raffaele Ponzini,Giovanna Rizzo,Marcello Cadioli,Antonio Esposito,Franco Maria Montevecchi,Alberto Redaelli +6 more
TL;DR: The hemodynamics within the aorta of five healthy humans were investigated and group analysis suggested that aortic helical blood flow dynamics is an emerging behavior that is common to normal individuals, and the results suggest that helical flow might be caused by natural optimization of fluid transport processes in the cardiovascular system.
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Inflow boundary conditions for image-based computational hemodynamics: Impact of idealized versus measured velocity profiles in the human aorta
TL;DR: It is concluded that the plausibility of the assumption of idealized velocity profiles as inlet BCs in personalized computational models can lead to misleading representations of the aortic hemodynamics both in terms of disturbed shear and bulk flow structures.
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Atherosclerosis at arterial bifurcations: evidence for the role of haemodynamics and geometry
Umberto Morbiducci,Annette M. Kok,Brenda R. Kwak,Peter Stone,David A. Steinman,Jolanda J. Wentzel +5 more
TL;DR: This review focuses on carotid and coronary bifurcations because of their primary relevance to stroke and heart attack and highlights reported relationships between atherosclerotic plaque location, progression and composition, and fluid forces at vessel's wall.