Dina Ralt

TL;DR: Evidence is obtained that attraction may be a key event in the fertilization process and may give an insight into the mechanism underlying early egg-sperm communication by showing that human spermatozoa accumulate in follicular fluid in vitro.

TL;DR: This is the first time that sperm chemotaxis and chemokinesis in response to a follicular factor(s) in mammals has been established and has been distinguished from other processes that might cause sperm accumulation.

TL;DR: If the in vitro results are representative of the physiological conditions in vivo, they imply that the role of sperm chemotaxis combined with enhanced motility may be to select capacitated spermatozoa and bring them to the egg.

TL;DR: Evidence is obtained that attraction may be a key event in the fertilization process and may give an insight into the mechanism underlying early egg-sperm communication by showing that human spermatozoa accumulate in follicular fluid in vitro.

TL;DR: It is reported that atrial natriuretic peptide (ANP), a known activator of particulate guanylate cyclase, induces attraction and swimming speed enhancement of human spermatozoa in vitro, and observations suggest either that an ANP-like substance is the physiological attractant for human spermutozoa, or, more likely, that ANP directly affects guany Late cyclase in a manner similar to that caused by the physiological attractingant.