D
Dipta Sengupta
Researcher at National Institute of Technology, Rourkela
Publications - 28
Citations - 924
Dipta Sengupta is an academic researcher from National Institute of Technology, Rourkela. The author has contributed to research in topics: Epigenetics & DNA methylation. The author has an hindex of 15, co-authored 28 publications receiving 710 citations.
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Green synthesis of silver nanoparticles using fresh water green alga Pithophora oedogonia (Mont.) Wittrock and evaluation of their antibacterial activity
TL;DR: In this paper, the aqueous extract of Pithophora oedogonia was used to produce silver nanoparticles (AgNPs) by reduction of silver nitrate.
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Histone deacetylases: a saga of perturbed acetylation homeostasis in cancer.
Sabnam Parbin,Swayamsiddha Kar,Arunima Shilpi,Dipta Sengupta,Moonmoon Deb,Sandip Kumar Rath,Samir Kumar Patra +6 more
TL;DR: This review summarizes the current knowledge of HDACs in tumorigenesis and tumor progression as well as their contribution to the hallmarks of cancer and discusses the potential role of histone deacetylase inhibitors as emerging epigenetic drugs to cure cancer.
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An insight into the various regulatory mechanisms modulating human DNA methyltransferase 1 stability and function
Swayamsiddha Kar,Moonmoon Deb,Dipta Sengupta,Arunima Shilpi,Sabnam Parbin,Jérôme Torrisani,Sriharsha Pradhan,Samir Kumar Patra +7 more
TL;DR: This review aims to provide a comprehensive account of the various regulatory mechanisms and interactions of DNMT1 so as to elucidate its function at the molecular level and understand the dynamics of DNA methylation at the cellular level.
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Expression profiling of DNA methylation-mediated epigenetic gene-silencing factors in breast cancer
Swayamsiddha Kar,Dipta Sengupta,Moonmoon Deb,Arunima Shilpi,Sabnam Parbin,Sandip Kumar Rath,Nibedita Pradhan,Madhumita Rakshit,Samir Kumar Patra +8 more
TL;DR: The epigenetic modulators AZA, TSA, SFN, and SAM may provide opportunities for cancer prevention by regulating the components of epigenetic gene-silencing machinery especially DNMTs and MBDs.
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Mechanisms of DNA methyltransferase-inhibitor interactions: Procyanidin B2 shows new promise for therapeutic intervention of cancer.
Arunima Shilpi,Sabnam Parbin,Dipta Sengupta,Swayamsiddha Kar,Moonmoon Deb,Sandip Kumar Rath,Nibedita Pradhan,Madhumita Rakshit,Samir Kumar Patra +8 more
TL;DR: In vitro analysis demonstrates the efficiency of procyanidin B2 in attenuating DNMT activity at IC50 of 6.88±0.647 μM and offers platform for pre-clinical trial and an insight to the treatment of cancer.