D
Dirk J. Reitsma
Researcher at Novartis
Publications - 19
Citations - 7843
Dirk J. Reitsma is an academic researcher from Novartis. The author has contributed to research in topics: Pamidronic acid & Breast cancer. The author has an hindex of 12, co-authored 19 publications receiving 7625 citations. Previous affiliations of Dirk J. Reitsma include University of California, Los Angeles & University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
The new bisphosphonate, Zometa (zoledronic acid), decreases skeletal complications in both osteolytic and osteoblastic lesions: a comparison to pamidronate.
Allan Lipton,Eric J. Small,Fred Saad,Donald M. Gleason,David Gordon,Matthew R. Smith,Lee S. Rosen,M. Ortu Kowalski,Dirk J. Reitsma,John J. Seaman +9 more
TL;DR: Zoledonic acid is the first bisphosphonate to demonstrate efficacy in both lytic and blastic disease and was well tolerated with a safety profile similar to other IV bisph phosphonates.
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Quantitation of interferon-induced Mx protein in whole blood lysates by an immunochemiluminescent assay: elimination of protease activity of cell lysates in toto.
Se-Kyung Oh,Stefan Luhowskyj,Patricia L. Witt,Paul S. Ritch,Dirk J. Reitsma,Harry Towbin,Michel A. Horisberger,Peter von Wussow,Barry I. Bluestein +8 more
TL;DR: availability of a reliable assay for Mx protein should facilitate the clinical evaluation of many of the newly constructed type-1 interferons, and this work has devised a new procedure both to maximize its solubility and virtually eliminate its proteolytic degradation.
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Alternative statistical strategies for biosimilar drug development
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Inhibition of growth of human breast cancer cell lines with the combination of zoledronic acid and a COX-2 inhibitor
L. Witters,M. Javeed,J. Crispino,J. Green,John J. Seaman,Dirk J. Reitsma,T. Kamal,Linda Engle,Vernon M. Chinchilli,Allan Lipton +9 more
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PP-8-8 Reduction of skeletal related complications in breast cancer patients with osteolytic bone metastases receiving hormone therapy, by monthly pamidronate sodium (AREDIA®) infusion
Richard L. Theriault,A. Upton,R. Leff,Stefan Glück,J. Stewart,S. Costello,J. Simeone,John J. Seaman,Robert Knight,M. Heffeman,Dirk J. Reitsma +10 more