D
Dominik R. Buell
Researcher at Max Planck Society
Publications - 7
Citations - 326
Dominik R. Buell is an academic researcher from Max Planck Society. The author has contributed to research in topics: Fluoxetine & Prefrontal cortex. The author has an hindex of 7, co-authored 7 publications receiving 287 citations.
Papers
More filters
Journal ArticleDOI
Intranasally Administered Neuropeptide S (NPS) Exerts Anxiolytic Effects Following Internalization Into NPS Receptor-Expressing Neurons
Irina A. Ionescu,Julien Dine,Yi-Chun Yen,Dominik R. Buell,Leonie Herrmann,Florian Holsboer,Matthias Eder,Rainer Landgraf,Ulrike Schmidt +8 more
TL;DR: The results not only enlighten the path of NPS in the brain, but also establish a non-invasive method for NPS administration in mice, thus strongly encouraging translation into a novel therapeutic approach for pathological anxiety in humans.
Journal ArticleDOI
Identification and characterization of HPA-axis reactivity endophenotypes in a cohort of female PTSD patients
Monika Zaba,Thomas Kirmeier,Irina A. Ionescu,Bastian Wollweber,Dominik R. Buell,Dominique J. Gall-Kleebach,Christine F. Schubert,Bozidar Novak,Christine Huber,Katharina Köhler,Florian Holsboer,Benno Pütz,Bertram Müller-Myhsok,Nina Höhne,Manfred Uhr,Marcus Ising,Leonie Herrmann,Ulrike Schmidt +17 more
TL;DR: HPA-axis reactivity endophenotypes are identified and characterized for the first time to offer an explanation for the inconsistent reports on HPA- axis function in PTSD and suggest that most likely other factors play a decisive role in determination of PTSD core symptom severity.
Journal ArticleDOI
Therapeutic Action of Fluoxetine is Associated with a Reduction in Prefrontal Cortical miR-1971 Expression Levels in a Mouse Model of Posttraumatic Stress Disorder.
Ulrike Schmidt,Leonie Herrmann,Kathrin Hagl,Bozidar Novak,Christine Huber,Florian Holsboer,Carsten T. Wotjak,Dominik R. Buell +7 more
TL;DR: It is suggested that traumatic stress and fluoxetine interact to cause distinct alterations in the mouse PFC miRNA signature in the long-term, as well as a significant reduction in mmu-miR-1971 expression.
Journal ArticleDOI
Long-Lasting Hippocampal Synaptic Protein Loss in a Mouse Model of Posttraumatic Stress Disorder
Leonie Herrmann,Irina A. Ionescu,Kathrin Henes,Yulia Golub,Nancy Xin Ru Wang,Dominik R. Buell,Florian Holsboer,Carsten T. Wotjak,Ulrike Schmidt +8 more
TL;DR: This study demonstrates for the first time that a loss of hippocampal synaptic proteins is associated with a PTSD-like syndrome in mice, and demonstrates that treatment with the serotonin reuptake inhibitor (SSRI) fluoxetine is able to counteract both the PTSD- like syndrome and the posttraumatic synaptic protein loss.
Journal ArticleDOI
miRNAs and other non-coding RNAs in posttraumatic stress disorder: a systematic review of clinical and animal studies
TL;DR: The first review on ncRNAs in PTSD is conducted and it is suggested that mir-132, which has been found to be regulated in three of the here included studies, as well as miRNAs with an already established role in Alzheimer's disease (AD) seem to be particularly promising candidates for future miRNA studies in PTSD.