D
Dominique Figarella-Branger
Researcher at Aix-Marseille University
Publications - 583
Citations - 39329
Dominique Figarella-Branger is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Medicine & Glioma. The author has an hindex of 80, co-authored 543 publications receiving 30147 citations. Previous affiliations of Dominique Figarella-Branger include Centre national de la recherche scientifique & University of the Mediterranean.
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Journal ArticleDOI
Molecular heterogeneity of glioblastomas: does location matter?
Emilie Denicolai,Emeline Tabouret,Carole Colin,Philippe Metellus,Isabelle Nanni,Celine Boucard,Aurélie Tchoghandjian,David Meyronet,Nathalie Baeza-Kallee,Olivier Chinot,Dominique Figarella-Branger +10 more
TL;DR: Data suggest a differential gene expression profile according to initial glioblastoma location, and among cortical locations, gene expressions were homogeneous while in contrast, periventricular locations exhibited distinct expression profiles.
Journal ArticleDOI
Multiplexed Droplet Digital PCR Assays for the Simultaneous Screening of Major Genetic Alterations in Tumors of the Central Nervous System.
Romain Appay,Frédéric Fina,Doriane Barets,Catherine Gallardo,Isabelle Nanni-Metellus,Didier Scavarda,Daniel Henaff,Juline Vincent,Lise Grewis,Philippe Pourquier,Carole Colin,Dominique Figarella-Branger +11 more
TL;DR: Five multiplexed dPCR assays to detect major CNS biomarkers by using only small amounts of DNA extracted from formalin-fixed paraffin-embedded specimens are described and it is believed that such strategies might help laboratories to optimize their screening strategies for routine diagnosis of pediatric and adult CNS tumors.
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Medulloblastomas associated with an APC germline pathogenic variant share the good prognosis of CTNNB1-mutated medulloblastomas.
Aurore Surun,Aurore Surun,Pascale Varlet,Laurence Brugières,Brigitte Lacour,Cécile Faure-Conter,Pierre Leblond,Anne-Isabelle Bertozzi-Salomon,Claire Berger,Nicolas André,Eric Sariban,Sandra Raimbault,Fabienne Prieur,Françoise Desseigne,Hélène Zattara,Rosine Guimbaud,Marc Polivka,Marie-Bernadette Delisle,Alexandre Vasiljevic,Claude-Alain Maurage,Dominique Figarella-Branger,Florence Coulet,Léa Guerrini-Rousseau,Claire Alapetite,Christelle Dufour,Chrystelle Colas,François Doz,François Doz,Franck Bourdeaut +28 more
TL;DR: The findings raise the question of applying de-escalation therapeutic protocol to treat patients with APC germline pathogenic variant given the excellent outcome, and reduced intensity of craniospinal irradiation may be further evaluated.
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CD44s and CD44v6 expression in localized T1-T2 conventional renal cell carcinomas.
Laurent Daniel,Eric Lechevallier,Roch Giorgi,Véronique Lindner,Marc de Fromont,Annick Vieillefond,Christian Coulange,Dominique Figarella-Branger +7 more
TL;DR: It is concluded that CD44s expression, but not CD44v6, is of potential prognostic interest in patients with localized T1–T2 conventional renal cell carcinomas.
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The French glioblastoma biobank (FGB): a national clinicobiological database
Anne Clavreul,Gwénaëlle Soulard,Jean-Michel Lemée,Marion Rigot,Pascale Fabbro-Peray,Luc Bauchet,Luc Bauchet,Dominique Figarella-Branger,Philippe Menei +8 more
TL;DR: A well-annotated clinicobiological database housing data and samples from GB patients has been set up in France and can support the large-scale translational projects required to improve GB care.