Dominique Michaud

TL;DR: This review describes protein N- and O-linked glycosylation in plants and highlights the limitations and advantages of plant-specific gly cosylation on plant-made biopharmaceuticals.

TL;DR: The current strategies proposed to minimize protein hydrolysis in plant protein factories are described, including organ‐specific transgene expression, organelle‐specific protein targeting, the grafting of stabilizing protein domains to labile proteins, protein secretion in natural fluids and the co‐expression of companion protease inhibitors.

TL;DR: This short review focuses on glycosylation and proteolytic processing of plant-made pharmaceuticals during their transport through the plant cell's secretory pathway and the practical implications of these important processes on the effectiveness of plant molecular pharming systems.

TL;DR: The results revealed that temperature strongly affected resistance, while UV-B did not, and the prevalence of dual symbiosis involving PAXS and H. defensa in local aphid populations suggests its importance in protecting aphid immunity to parasitism under abiotic stress.

TL;DR: Interestingly, beetles fed foliage expressing the highest level of OCI reacted rapidly to the presence ofOCI by producing OCI-insensitive proteases, and exhibiting strong hypertrophic behavior by ingestion of 2.4-2.5 times more OCI rich foliage apparently as a compensatory response for nutritional stress due to the protease inhibitor in their diet.