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Donald T. Campbell
Researcher at Oregon State University
Publications - 6
Citations - 337
Donald T. Campbell is an academic researcher from Oregon State University. The author has contributed to research in topics: Sodium channel & Voltage clamp. The author has an hindex of 6, co-authored 6 publications receiving 328 citations. Previous affiliations of Donald T. Campbell include University of Iowa.
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Journal ArticleDOI
Na channels in skeletal muscle concentrated near the neuromuscular junction
TL;DR: The distribution in muscle of the voltage-gated Na channel responsible for the action potential is explored using the loose patch-clamp technique, and Na currents in 5–10 µm-diameter membrane patches are measured as a function of distance from the end plate region of snake and rat muscle fibres.
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Na channel distribution in vertebrate skeletal muscle.
TL;DR: It is concluded that Na channels are abundant in the endplate and near- endplate membrane and are sparse close to the tendon and tested the ability of tetrodotoxin to block Na current in regions close to and far from the end plate and found no evidence for toxin-resistant channels in either region.
Journal ArticleDOI
Ionic selectivity of the sodium channel of frog skeletal muscle.
TL;DR: The ionic selectivity of the Na channel to a variety of metal and organic cations is studied in frog semitendinosus muscle and results suggest that the selectivity filter of the two channels is the same.
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Large and small vertebrate sensory neurons express different Na and K channel subtypes.
TL;DR: The contributions of these channel subtypes to the electrical properties of sensory neurons were investigated under conditions that minimized the contribution of Ca current.
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Modified kinetics and selectivity of sodium channels in frog skeletal muscle fibers treated with aconitine.
TL;DR: The results suggest that sites other than those involved in channel block by protons and TTX are important in determining sodium channel selectivity.