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Dorothy Kyeyune
Researcher at Makerere University
Publications - 12
Citations - 291
Dorothy Kyeyune is an academic researcher from Makerere University. The author has contributed to research in topics: Blood transfusion & Anemia. The author has an hindex of 5, co-authored 10 publications receiving 222 citations.
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Journal ArticleDOI
Effect of Transfusion of Red Blood Cells With Longer vs Shorter Storage Duration on Elevated Blood Lactate Levels in Children With Severe Anemia: The TOTAL Randomized Clinical Trial
Aggrey Dhabangi,Brenda Ainomugisha,Christine Cserti-Gazdewich,Henry Ddungu,Dorothy Kyeyune,Ezra Musisi,Robert O. Opoka,Christopher P. Stowell,Walter H. Dzik +8 more
TL;DR: Among children with lactic acidosis due to severe anemia, transfusion of longer-storage compared with shorter-storage RBC units did not result in inferior reduction of elevated blood lactate levels, and these findings have relevance regarding the efficacy of stored RBC transfusion for patients with critical tissue hypoxia and lactic acids due to anemia.
Journal ArticleDOI
Transfusion and Treatment of severe anaemia in African children (TRACT): a study protocol for a randomised controlled trial
Ayub Mpoya,Sarah Kiguli,Peter Olupot-Olupot,Robert O. Opoka,Charles Engoru,Macpherson Mallewa,Yami Chimalizeni,Neil Kennedy,Dorothy Kyeyune,Benjamin Wabwire,Bridon M'baya,Imelda Bates,Imelda Bates,Britta C. Urban,Britta C. Urban,Michael Boele von Hensbroek,Robert S. Heyderman,Robert S. Heyderman,Margaret J. Thomason,Sophie Uyoga,Thomas N. Williams,Diana M. Gibb,Elizabeth C. George,A. Sarah Walker,Kathryn Maitland +24 more
TL;DR: If confirmed by the trial, a cheap and widely available ‘bundle’ of effective interventions, directed at immediate and downstream consequences of severe anaemia, could lead to substantial reductions in mortality in a substantial number of African children hospitalised withsevere anaemia every year, if widely implemented.
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Cerebral Oximetry in Ugandan Children With Severe Anemia: Clinical Categories and Response to Transfusion.
Aggrey Dhabangi,Brenda Ainomugisha,Christine Cserti-Gazdewich,Henry Ddungu,Dorothy Kyeyune,Ezra Musisi,Robert O. Opoka,Christopher P. Stowell,Walter H. Dzik +8 more
TL;DR: The level of consciousness, hemoglobin concentration, blood lactate level, and thigh muscle tSo2 level were poor predictors of cerebral oxygen saturation, and more studies are needed to evaluate the use of noninvasive cerebral tissue oximetry in the care of children with severe anemia.
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Efficacy of convalescent plasma for treatment of COVID-19 in Uganda.
Bruce Kirenga,Pauline Byakika-Kibwika,Winters Muttamba,Alex Kayongo,Namakula Olive Loryndah,Levicatus Mugenyi,Noah Kiwanuka,John Lusiba,Angella Atukunda,Raymond Mugume,Francis Ssali,Henry Ddungu,Winceslaus Katagira,Rogers Sekibira,Cissy Kityo,Dorothy Kyeyune,Susan Acana,Hellen Aanyu-Tukamuhebwa,Wilberforce Kabweru,Fred Nakwagala,Bernard Sentalo Bagaya,Ivan Kimuli,Rebecca Nantanda,Esther Buregyeya,Baterana Byarugaba,Charles Olaro,Henry Mwebesa,Moses Joloba,Trishul Siddharthan,William Bazeyo +29 more
TL;DR: In this article, the efficacy of CCP for treatment of COVID-19 in Uganda was evaluated in a randomized trial, where patients with positive SARS-CoV-2 reverse transcriptase (RT)-PCR test irrespective of disease severity were hospitalised and randomised to receive either CCP plus standard of care (SOC) or SOC alone.
Journal ArticleDOI
Transfusion Medicine in Sub-Saharan Africa: Conference Summary.
Walter Sunny Dzik,Dorothy Kyeyune,Grace Otekat,Bernard Natukunda,Heather A. Hume,Phillip Kasirye,Henry Ddungu,Isaac Kajja,Aggrey Dhabangi,Godfrey R Mugyenyi,Claire M Seguin,Linda Barnes,Meghan Delaney +12 more
TL;DR: In November 2014, a 3-day conference devoted to transfusion medicine in sub-Saharan Africa was held in Kampala, Uganda, with a broad overview of issues pertinent to transfusions medicine in Africa.