D
Douglas W. Oliver
Researcher at North-West University
Publications - 58
Citations - 935
Douglas W. Oliver is an academic researcher from North-West University. The author has contributed to research in topics: Cerebral blood flow & Acetazolamide. The author has an hindex of 15, co-authored 58 publications receiving 868 citations. Previous affiliations of Douglas W. Oliver include Potchefstroom University for Christian Higher Education & University College West.
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South African traditional herbal medicines used during pregnancy and childbirth.
TL;DR: The ethnic background and traditional usage of these remedies was researched and a literature survey revealed that 57 different plants were used in herbal remedies during pregnancy and childbirth.
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Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease.
Jacques Joubert,Germaine B. Foka,Benjamin P. Repsold,Douglas W. Oliver,Erika Kapp,Sarel F. Malan +5 more
TL;DR: Molecular modeling revealed that 19 was able to bind simultaneously to the CAS, mid-gorge and PAS sites of AChE and BuChE suggesting that it will be able to inhibit AchE induced Aβ aggregation.
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Polycyclic cage structures as lipophilic scaffolds for neuroactive drugs.
Jacques Joubert,Jacques Joubert,Werner J. Geldenhuys,Cornelis J. Van der Schyf,Douglas W. Oliver,Hendrik G. Kruger,Thavendran Govender,Sarel F. Malan +7 more
TL;DR: This Minireview focuses on the recent developments in the field of polycyclic cage compounds, as well as the relationship between the lipophilic character of these cage‐derived drugs and the ability of such compounds to target and reach the CNS and improve the pharmacodynamic properties of compounds conjugated to it.
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Recent advances in drug action and therapeutics: Relevance of novel concepts in G-protein-coupled receptor and signal transduction pharmacology
TL;DR: The understanding of molecular receptor and signal transduction pharmacology enables clinicians to improve their effective implementation of current and future pharmacotherapy, ultimately enhancing the quality of life of their patients.
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Synthesis and biological activity of D3-trishomocubyl-4-amines.
TL;DR: Weak to mild anticholinergic properties were observed during the reduction of oxotremorine induced tremor and salivation procedure and acute toxicities similar to that of amantadine were observed for some of these compounds.