Electrochemical biosensors for pathogen detection

The efficient handling of wastewater pollutants is a must, since they are continuously defiling limited fresh water resources, seriously affecting the terrestrial, aquatic, and aerial flora and fauna. Our vision is to undertake an exhaustive examination of current research trends with a focus on nanomaterials (NMs) to considerably improve the performance of classical wastewater treatment technologies, e.g. adsorption, catalysis, separation, and disinfection. Additionally, NM-based sensor technologies are considered, since they have been significantly used for monitoring water contaminants. We also suggest future directions to inform investigators of potentially disruptive NM technologies that have to be investigated in more detail. The fate and environmental transformations of NMs, which need to be addressed before large-scale implementation of NMs for water purification, are also highlighted.

Recent advances in nanomaterials for water protection and monitoring.

Magnetic nanoparticles (MNPs) have attracted a growing interest in the development and fabrication of sensors and biosensors for several applications. MNPs can be integrated into the transducer materials and/or be dispersed in the sample followed by their attraction by an external magnetic field onto the active detection surface of the (bio)sensor. This review describes and discusses the recent applications of MNPs in sensors and biosensors, taking into consideration their analytical figures of merit. This work also addresses the future trends and perspectives of sensors and biosensors based on MNPs.

https://blog.ub.ac.id/andies/files/2014/12/KELP-7-Sensors-and-biosensors-based-on-magnetic-nanoparticles.pdf

Sensors and biosensors based on magnetic nanoparticles

Methods for the detection and determination of nitrite and nitrate: A review.

Recent advances in nanomaterial-based biosensors for antibiotics detection.

An electrochemical aptasensor based on gold nanoparticles dotted graphene modified glassy carbon electrode for label-free detection of bisphenol A in milk samples.

Herein, we present a simple electrochemical tetracycline (TET) aptasensor with multi-walled carbon nanotubes (MWCNTs) modification. MWCNTs were dropped on the glassy carbon electrode (GCE) to immobilize the anti-TET aptamer and to construct the aptasensor. The stepwise assembly process of the aptasensor was characterized by cyclic voltammetry. Results demonstrated that the peak currents of Fe(CN) 6 3− /Fe(CN) 6 4− redox pair decreased due to the formation of anti-TET/TET complexes on the modified electrode. The optimization of the loading amount of MWCNTs, the incubating conditions of aptamer and the detection time of TET were investigated in details. Under optimal conditions, the peak currents change obtained by DPV increased linearly with the increasing TET concentrations in the range from 1 × 10 −8  M to 5 × 10 −5  M with a linear coefficiency of 0.995. This electrochemical aptasensor has a detection limit of 5 × 10 −9  M and was successfully applied to the determination of TET in spiked milk samples.

Electrochemical aptasensor for the detection of tetracycline with multi-walled carbon nanotubes amplification

A nanobeads amplified QCM immunosensor for the detection of avian influenza virus H5N1.

A novel carbon composite electrode has been fabricated using ionic liquid n-octylpyridinum hexafluorophosphate (OPFP) and single-walled carbon nanotube (SWCNT). This electrode combined the advantages of ionic liquid and SWCNT as well as the characteristics of the “bulk” composite electrodes. Compared with the commercial glassy carbon electrode (GCE) and the ionic liquid–graphite (IL-G) composite electrode, the ionic liquid–SWCNT (IL-SWCNT) composite electrode exhibited remarkable increase in the electron transfer rate for electroactive compound and significant decrease in the overpotential for the oxidation of nitrite. Based on the enhanced electrocatalytic activity for the oxidation of nitrite, a wide linear range from 1.0 μM to 12.0 mM with a low detection limit of 0.1 μM was obtained. Furthermore, the IL-SWCNT electrode was applied to determine nitrite levels in milk samples. Experimental results showed that the proposed electrode could be used as an effective and sensitive sensor for the determination of nitrite.

Dujuan Li

Papers

An electrochemical aptasensor based on gold nanoparticles dotted graphene modified glassy carbon electrode for label-free detection of bisphenol A in milk samples.

Electrochemical aptasensor for the detection of tetracycline with multi-walled carbon nanotubes amplification

A nanobeads amplified QCM immunosensor for the detection of avian influenza virus H5N1.

An amperometric sensor based on ionic liquid and carbon nanotube modified composite electrode for the determination of nitrite in milk

Label-free capacitive immunosensor based on quartz crystal Au electrode for rapid and sensitive detection of Escherichia coli O157:H7