D
Dung-Tsa Chen
Researcher at Moffitt Cancer Center
Publications - 96
Citations - 2691
Dung-Tsa Chen is an academic researcher from Moffitt Cancer Center. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 23, co-authored 76 publications receiving 2127 citations.
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Journal ArticleDOI
Therapeutic regulation of myeloid-derived suppressor cells and immune response to cancer vaccine in patients with extensive stage small cell lung cancer
TL;DR: Depletion of MDSC substantially improved the immune response to vaccination, suggesting that this approach can be used to enhance the effect of immune interventions in cancer.
Journal ArticleDOI
PET/CT Fusion Scan Enhances CT Staging in Patients with Pancreatic Neoplasms
Jeffrey M. Farma,Alfredo A. Santillan,Marcovalerio Melis,Janet Walters,Daly Belinc,Dung-Tsa Chen,Edward A. Eikman,Mokenge P. Malafa +7 more
TL;DR: PET/CT increased sensitivity for detection of metastatic disease when combined with standard CT and influenced the clinical management in 11% of patients with invasive cancer.
Journal ArticleDOI
MicroRNAs and their target messenger RNAs associated with endometrial carcinogenesis.
Todd Boren,Yin Xiong,Ardeshir Hakam,Robert M. Wenham,Sachin M. Apte,Zhengzheng Wei,Siddharth G. Kamath,Dung-Tsa Chen,Holly K. Dressman,Johnathan M. Lancaster +9 more
TL;DR: The strategy of integrating miRNA/mRNA data may also aid in the identification of important biologic pathways and additional unique genes that have importance in endometrial pathogenesis.
Journal ArticleDOI
Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue
Dung-Tsa Chen,Aejaz Nasir,Aedín C. Culhane,Chinnambally Venkataramu,William J. Fulp,Renee Rubio,Tao Wang,Deepak Agrawal,Susan McCarthy,Mike Gruidl,Gregory C. Bloom,Tove Anderson,Joseph White,John Quackenbush,Timothy J. Yeatman +14 more
TL;DR: The discovery of a “malignancy-risk” gene signature that may portend risk of breast cancer development in benign, but molecularly-abnormal, breast tissue is reported.
Journal ArticleDOI
MicroRNAs and their target messenger RNAs associated with ovarian cancer response to chemotherapy
Todd Boren,Yin Xiong,Ardeshir Hakam,Robert M. Wenham,Sachin M. Apte,Gina Chan,Siddharth G. Kamath,Dung-Tsa Chen,Holly K. Dressman,Johnathan M. Lancaster +9 more
TL;DR: The strategy of integrating miRNA and mRNA data may aid in the characterization of important molecular pathways associated with OVCA chemo-response.