http://www.ifc.unam.mx/curso_ritmos/capitulo10/Welsh.pdf

Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms

The most characteristic property of microglia is their swift activation in response to neuronal stress and their capacity for site-directed phagocytosis. The transformation of microglia into intrinsic brain macrophages appears to be under strict control and takes place if neuronal and/or terminal degeneration occurs in response to nerve lesion. The differentiation of microglia into brain macrophages is accompanied by the release of several secretory products, e.g., proteinases, cytokines, reactive oxygen intermediates, and reactive nitrogen intermediates. Interference with the microglial activation or the productions of cytotoxic metabolites by microglia may thus offer new therapeutic opportunities for the prevention of neuronal cell death in CNS disease.

Cytotoxicity of microglia

Junctional intercellular communication and the control of growth

Immortalization of murine microglial cells by a v-raf / v-myc carrying retrovirus

The design and use of materials in the nanoscale size range for addressing medical and health-related issues continues to receive increasing interest. Research in nanomedicine spans a multitude of areas, including drug delivery, vaccine development, antibacterial, diagnosis and imaging tools, wearable devices, implants, high-throughput screening platforms, etc. using biological, nonbiological, biomimetic, or hybrid materials. Many of these developments are starting to be translated into viable clinical products. Here, we provide an overview of recent developments in nanomedicine and highlight the current challenges and upcoming opportunities for the field and translation to the clinic.

/pdf/diverse-applications-of-nanomedicine-2vhw6mihkp.pdf

Diverse Applications of Nanomedicine

A new fixed-array multi-microelectrode system designed for long-term monitoring of extracellular single unit neuronal activity in vitro.

Microglia and microglia-derived brain macrophages in culture: generation from axotomized rat facial nuclei, identification and characterization in vitro.

E. Rieske

Papers

A new fixed-array multi-microelectrode system designed for long-term monitoring of extracellular single unit neuronal activity in vitro.

Microglia and microglia-derived brain macrophages in culture: generation from axotomized rat facial nuclei, identification and characterization in vitro.

Transfer of radioactive material between electrically coupled neurons of the leech central nervous system.

Intradendritic transport to postsynaptic sites

Neurite regeneration after cell surgery with laser microbeam irradiation