E. Sylvester Vizi

TL;DR: The enzymatic activities of CD39 and CD73 play strategic roles in calibrating the duration, magnitude, and chemical nature of purinergic signals delivered to immune cells through the conversion of ADP/ATP to AMP and AMP to adenosine, suggesting these ectoenzymes are novel therapeutic targets for managing a variety of disorders.

TL;DR: In this paper, the structural and pharmacological features of the P2X7 receptor, as well as its cell-type specific localization in the nervous system are reviewed. And the participation of P2x7 receptors in distinct neuronal, astroglial and microglial functions are described.

TL;DR: This is the first neurochemical evidence that the activation of CB1 cannabinoid receptors leads to the augmentation of [(3)H]dopamine efflux via a local GABA(A) receptor-mediated disinhibitory mechanism in the rat nucleus accumbens.

TL;DR: Evidence that long‐term potentiation is indeed boosted by stimulation of dendritic α7‐nAChRs is provided and a new mechanism for a cholinergic switch in memory encoding and retrieval is suggested.

TL;DR: Effects of local anesthetics on resting catecholamine release in the spinal cord may contribute to their action during neuropathic pain relief and spinal analgesia as well as to their side effects in the CNS.