G
György Haskó
Researcher at Columbia University
Publications - 224
Citations - 21830
György Haskó is an academic researcher from Columbia University. The author has contributed to research in topics: Adenosine & Inflammation. The author has an hindex of 78, co-authored 210 publications receiving 19160 citations. Previous affiliations of György Haskó include University of Medicine and Dentistry of New Jersey & National Institutes of Health.
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Adenosine receptors: therapeutic aspects for inflammatory and immune diseases
TL;DR: This work has generated excitement regarding the potential use of adenosine-receptor-based therapies in the treatment of infection, autoimmunity, ischaemia and degenerative diseases.
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CD39 and CD73 in immunity and inflammation
TL;DR: The enzymatic activities of CD39 and CD73 play strategic roles in calibrating the duration, magnitude, and chemical nature of purinergic signals delivered to immune cells through the conversion of ADP/ATP to AMP and AMP to adenosine, suggesting these ectoenzymes are novel therapeutic targets for managing a variety of disorders.
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Adenosine: an endogenous regulator of innate immunity
TL;DR: Adenosine, a purine nucleoside that is elaborated at injured and inflamed sites, has a central role in the regulation of inflammatory responses and in limiting inflammatory tissue destruction.
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NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential
Oleg V. Evgenov,Pal Pacher,Peter Schmidt,György Haskó,Harald H.H.W. Schmidt,Johannes-Peter Stasch +5 more
TL;DR: The discovery, biochemistry, pharmacology and clinical potential of haem-dependent sGC stimulators andHaem-independent sGC activators are reviewed.
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Immunity, inflammation and cancer: a leading role for adenosine
TL;DR: The role of adenosine and its receptors in regulating the complex interplay among immune, inflammatory, endothelial and cancer cells during the course of neoplastic disease is critically discussed.