E
Earl Homsher
Researcher at University of California, Los Angeles
Publications - 51
Citations - 4536
Earl Homsher is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Myosin & Actin. The author has an hindex of 30, co-authored 51 publications receiving 4347 citations. Previous affiliations of Earl Homsher include Oklahoma State University Center for Health Sciences & National Institutes of Health.
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Journal ArticleDOI
Regulation of Contraction in Striated Muscle
TL;DR: Ca(2+) regulation of contraction in vertebrate striated muscle is exerted primarily through effects on the thin filament, which regulate strong cross-bridge binding to actin, and the physiological observations of steady-state and transient mechanical behavior are supported.
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The effect of phosphate and calcium on force generation in glycerinated rabbit skeletal muscle fibers. A steady-state and transient kinetic study.
N C Millar,Earl Homsher +1 more
TL;DR: Steady-state results show that the three parameters that define the force-pCa relation all vary linearly with log [Pi], and can be interpreted in terms of a model in which strong cross-bridges activate the thin filament, this activation being modulated by Ca2+ binding to troponin.
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Activation heat, activation metabolism and tension-related heat in frog semitendinosus muscles
TL;DR: Frog semitendinosus muscles were stretched to various lengths beyond the rest length and their initial heat and isometric tension production were measured.
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Force Generation in Single Conventional Actomyosin Complexes under High Dynamic Load
TL;DR: The results indicate that single myosin molecules transduce energy nearly as efficiently as whole muscle and that the mechanical control of the ATP hydrolysis rate is in part exerted by reversal of the force-generating actomyosin transition under high load without net utilization of ATP.
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Skeletal and Cardiac Muscle Contractile Activation: Tropomyosin “Rocks and Rolls”
TL;DR: Variations in activation properties account for functional differences between these muscle types in skeletal and cardiac muscle.