E
Edésia Martins Barros de Sousa
Researcher at National Nuclear Energy Commission
Publications - 69
Citations - 2406
Edésia Martins Barros de Sousa is an academic researcher from National Nuclear Energy Commission. The author has contributed to research in topics: Mesoporous silica & Mesoporous material. The author has an hindex of 26, co-authored 61 publications receiving 2165 citations. Previous affiliations of Edésia Martins Barros de Sousa include Complutense University of Madrid & Universidade Federal de Minas Gerais.
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Journal ArticleDOI
Mesoporous SBA-15 HPLC evaluation for controlled gentamicin drug delivery.
Antonio L. Doadrio,Edésia Martins Barros de Sousa,J.C. Doadrio,J. Pérez Pariente,Isabel Izquierdo-Barba,María Vallet-Regí +5 more
TL;DR: A new HPLC method was employed for calculated gentamicin amount in the delivery test, which requires a small amount of sample, very advisable in these kinds of assays.
Journal ArticleDOI
Functionalization of mesoporous materials with long alkyl chains as a strategy for controlling drug delivery pattern
J.C. Doadrio,Edésia Martins Barros de Sousa,Isabel Izquierdo-Barba,Antonio L. Doadrio,Joaquín Pérez-Pariente,María Vallet-Regí +5 more
TL;DR: Mesoporous silica SBA-15 was prepared to evaluate its effectiveness as a matrix for the controlled delivery of macrolide-type antibiotics, and two types of material were used to evaluate the delivery.
Journal ArticleDOI
Influence of mesoporous structure type on the controlled delivery of drugs: release of ibuprofen from MCM-48, SBA-15 and functionalized SBA-15
Isabel Izquierdo-Barba,Edésia Martins Barros de Sousa,J.C. Doadrio,Antonio L. Doadrio,Joaquín Pérez Pariente,Africa Martínez,Florence Babonneau,María Vallet-Regí +7 more
TL;DR: In this article, mesoporous materials such as MCM-48 and SBA-15, which present different pore sizes (3.7 and 8.8 nm) and structural characteristics (3D-bicontinuous cubic and 2D-hexagonal, respectively) have been synthesized to evaluate their application as drug delivery system and to determine their influence on release kinetic of ibuprofen.
Journal ArticleDOI
Mesoporous silica/apatite nanocomposite: Special synthesis route to control local drug delivery
TL;DR: The influence of the release rate of atenolol molecules from pure MCM-41 mesoporous and containing hydroxyapatite was demonstrated, since it results in a very slowly drug delivery from the nanocomposite system.
Journal ArticleDOI
Multifunctional mesoporous silica nanoparticles for cancer-targeted, controlled drug delivery and imaging
Luiza Baptista de Oliveira Freitas,Laura de Melo Corgosinho,Jerusa Araújo Quintão Arantes Faria,V.M. Santos,Jarbas M. Resende,Alexandre Soares Leal,Dawidson Assis Gomes,Edésia Martins Barros de Sousa +7 more
TL;DR: It is believed that the multifunctional silica-based theranostic system could serve as a platform for cancer-targeted, controlled drug delivery and PET imaging to be applied in cancer therapy.