Edoardo Calderini

TL;DR: The effects of inspiratory flow rate and inflation volume on the resistive properties of the total respiratory system were investigated in 16 anesthetized paralyzed humans by using the technique of rapid airway occlusion during constant flow inflation to measure the intrinsic resistance and effective additional resistance as the result of viscoelastic pressure dissipations within the pulmonary and chest wall tissues.

TL;DR: In the presence of air leaks a time-cycled expiratory trigger provides a better patient-machine interaction than a flow- cycled expIRatory trigger during NIPSV.

TL;DR: Pulmonary and chest wall mechanics were studied in 18 anesthetized paralyzed supine humans by use of the technique of rapid airway occlusion during constant-flow inflation and found that Static and dynamic elastances, as well as delta R, were higher for the lung than for the chest wall.

TL;DR: These recommendations should help to harmonise the approach to paediatric mechanical ventilation and can be proposed as a standard-of-care applicable in daily clinical practice and clinical research.

TL;DR: The PM significantly reduced skin breakdown while improving patient comfort, compared to the CMs, in a randomized study of patients with acute respiratory failure during non-invasive ventilation.