E
Eduard Denisov
Researcher at Thermo Fisher Scientific
Publications - 59
Citations - 4469
Eduard Denisov is an academic researcher from Thermo Fisher Scientific. The author has contributed to research in topics: Orbitrap & Mass spectrometry. The author has an hindex of 21, co-authored 55 publications receiving 4126 citations. Previous affiliations of Eduard Denisov include Environmental Molecular Sciences Laboratory & Thermo Electron.
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Journal ArticleDOI
Performance evaluation of a hybrid linear ion trap/orbitrap mass spectrometer.
Alexander Makarov,Eduard Denisov,Alexander Kholomeev,Wilko Balschun,Oliver Lange,Kerstin Strupat,Stevan Horning +6 more
TL;DR: Rapid, automated data-dependent capabilities enable real-time acquisition of up to three high-mass accuracy MS/MS spectra per second.
Journal ArticleDOI
A Dual Pressure Linear Ion Trap Orbitrap Instrument with Very High Sequencing Speed
Jesper V. Olsen,Jae C. Schwartz,Jens Griep-Raming,Michael L. Nielsen,Eugen Damoc,Eduard Denisov,Oliver Lange,Philip M. Remes,Dennis M. Taylor,Maurizio Splendore,Eloy R. Wouters,Michael W. Senko,Alexander Makarov,Matthias Mann,Stevan Horning +14 more
TL;DR: A next generation LTQ Orbitrap system termed Velos is described, with significantly increased sensitivity and scan speed, and an improved higher-energy collisional dissociation cell with increased ion extraction capabilities was implemented.
Journal ArticleDOI
Dynamic range of mass accuracy in LTQ orbitrap hybrid mass spectrometer
TL;DR: It was shown that 5-ppm mass accuracy of the orbitrap mass analyzer is reached with >95% probability at a dynamic range of more than 5000, which is at least an order of magnitude higher than typical values for time-of-flight instruments.
Journal ArticleDOI
Ultra High Resolution Linear Ion Trap Orbitrap Mass Spectrometer (Orbitrap Elite) Facilitates Top Down LC MS/MS and Versatile Peptide Fragmentation Modes
Annette Michalski,Eugen Damoc,Oliver Lange,Eduard Denisov,Dirk Nolting,Mathias Müller,Rosa Viner,Jae C. Schwartz,Philip M. Remes,Michael W. Belford,Jean-Jacques Dunyach,Juergen Cox,Stevan Horning,Matthias Mann,Alexander Makarov +14 more
TL;DR: A novel version of this instrument family, the Orbitrap Elite, which is improved in three main areas: the ion transfer optics has an ion path that blocks the line of sight to achieve more robust operation, the tandem MS acquisition speed of the dual cell linear ion trap now exceeds 12 Hz, and the resolving power of the orbitrap analyzer has been increased twofold.
Journal ArticleDOI
High-sensitivity Orbitrap mass analysis of intact macromolecular assemblies.
TL;DR: The Orbitrap mass analyzer can be used to measure protein assemblies of molecular weights approaching one megadalton with sensitivity down to the detection of single ions with outstanding mass-spectral resolution.