Showing papers by "Eduard Maron published in 2019"
Imperial College London1, Southern Health NHS Foundation Trust2, University of Tartu3, University of Bologna4, Mahatma Gandhi University5, King's College London6, University of Western Australia7, Tampere University of Technology8, University of Tampere9, Medical University of Vienna10, Palacký University, Olomouc11, University of Eastern Finland12, Nanyang Technological University13, Tallinn University of Technology14, Ludwig Maximilian University of Munich15, Sheba Medical Center16, Carlos III Health Institute17, Paris Descartes University18, Maastricht University19, Lund University20
TL;DR: Current mental health services across the world remain expert-centric and are based on traditional workflows, mostly using impractical and ineffective electronic record systems or even paper-based systems, according to the World Health Organization.
Abstract: Current mental health services across the world remain expert-centric and are based on traditional workflows, mostly using impractical and ineffective electronic record systems or even paper-based ...
12 citations
01 Jan 2019
TL;DR: The current state of pharmacogenomics of several mental health disorders is reviewed including latest results from candidate genes and genome-wide association studies, and incorporation of genetic factors into treatment algorithms is reviewed.
Abstract: However, there is strong belief that further search for genetic factors underlying treatment response, which are also defined as “treatment biomarkers,” would contribute to the personalized medicine approach, in which biomarkers would guide decision-making and help to select the most suitable medication for individual patients. Moreover, incorporation of genetic factors into treatment algorithms could speed recovery from disease by shortening or eliminating lengthy and ineffective trials and thus reduce the risk of treatment resistance. In this chapter, we review the current state of pharmacogenomics of several mental health disorders including latest results from candidate genes and genome-wide association studies. Although a host of genes has been explored in psychiatry, only small numbers of replicated findings have emerged so far. The sample sizes and heterogeneous phenotype definition may be considered the major impediments to success in this important field.