E
Eduardo Habib Bechelane Maia
Researcher at Centro Federal de Educação Tecnológica de Minas Gerais
Publications - 9
Citations - 327
Eduardo Habib Bechelane Maia is an academic researcher from Centro Federal de Educação Tecnológica de Minas Gerais. The author has contributed to research in topics: Virtual screening & Context (language use). The author has an hindex of 5, co-authored 7 publications receiving 86 citations. Previous affiliations of Eduardo Habib Bechelane Maia include Universidade Tecnológica Federal do Paraná, Medianeira & Universidade Federal de São João del-Rei.
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Journal ArticleDOI
Structure-Based Virtual Screening: From Classical to Artificial Intelligence.
Eduardo Habib Bechelane Maia,Eduardo Habib Bechelane Maia,Letícia Cristina Assis,Tiago Alves de Oliveira,Alisson Marques Silva,Alex Gutterres Taranto +5 more
TL;DR: An overview of the challenges involved in the use of CADD to performSBVS, the areas where CADD tools support SBVS, a comparison between the most commonly used tools, and the techniques currently used in an attempt to reduce the time and cost in the drug development process are presented.
Journal ArticleDOI
Immunoinformatics Design of Multi-Epitope Peptide-Based Vaccine Against Schistosoma mansoni Using Transmembrane Proteins as a Target.
Rodrigo C. O. Sanches,Sandeep Tiwari,Laís Cunha Grossi Ferreira,Flávio Martins de Oliveira,Marcelo Donizete Lopes,Maria Juliana Ferreira Passos,Eduardo Habib Bechelane Maia,Eduardo Habib Bechelane Maia,Alex Gutterres Taranto,Rodrigo Bentes Kato,Vasco Azevedo,Débora de Oliveira Lopes +11 more
TL;DR: In this article, a robust immunoinformatics approach, targeting S. mansoni transmembrane proteins, was applied to construct a chimeric antigen, and the final chimeric multi-epitope vaccine was predicted as prone to induce B-cell and IFN-γ based immunity.
Journal ArticleDOI
Molecular Architect: A User-Friendly Workflow for Virtual Screening.
Eduardo Habib Bechelane Maia,Eduardo Habib Bechelane Maia,Lucas Rolim Medaglia,Alisson Marques Silva,Alex Gutterres Taranto +4 more
TL;DR: MolAr is a workflow with a simple and intuitive interface that acts in an integrated and automated form to perform the entire VS process, from protein preparation (homology modeling and protonation state) to virtual screening.
Journal ArticleDOI
Octopus: a platform for the virtual high-throughput screening of a pool of compounds against a set of molecular targets.
Eduardo Habib Bechelane Maia,Eduardo Habib Bechelane Maia,Vinícius Alves Campos,Vinícius Alves Campos,Bianca dos Reis Santos,Bianca dos Reis Santos,Marina Santos Costa,Marina Santos Costa,Iann Gabriel Lima,Iann Gabriel Lima,Sandro J. Greco,Rosy Iara Maciel de Azambuja Ribeiro,Felipe M. Munayer,Alisson Marques Silva,Alex Gutterres Taranto +14 more
TL;DR: Octopus is an automated workflow management tool that is scalable for virtual high-throughput screening (vHTS) and a platform for inverse virtual screening (IVS) to search new molecular targets for drugs.
Journal ArticleDOI
Brazilian malaria molecular targets (BraMMT): selected receptors for virtual high-throughput screening experiments.
Renata Rachide Nunes,Amanda Luisa da Fonseca,Ana Claudia de Souza Pinto,Eduardo Habib Bechelane Maia,Alisson Marques Silva,Fernando de Pilla Varotti,Alex Gutterres Taranto +6 more
TL;DR: The BraMMT is available to perform vHTS experiments using OCTOPUS or Raccoon software to improve the search for new antimalarial compounds and suggested a new pharmacological mechanism for quinine, which includes inhibition of falcipain-II and a potential new anti-malaria candidate, clioquinol.