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Elba Villegas
Researcher at Universidad Autónoma del Estado de Morelos
Publications - 45
Citations - 1396
Elba Villegas is an academic researcher from Universidad Autónoma del Estado de Morelos. The author has contributed to research in topics: Antimicrobial & Spider toxin. The author has an hindex of 22, co-authored 45 publications receiving 1271 citations. Previous affiliations of Elba Villegas include Universidad Autónoma del Estado de México & Universidad Autónoma Metropolitana.
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Journal ArticleDOI
Characterization of unique amphipathic antimicrobial peptides from venom of the scorpion Pandinus imperator.
Gerardo Corzo,Pierre Escoubas,Elba Villegas,Kevin J. Barnham,Weilan He,Raymond S. Norton,Terumi Nakajima +6 more
TL;DR: The first report of magainin-type polycationic antimicrobial peptides in scorpion venom is reported, which brings new insights into the mode of action of scorpions venom and also opens new avenues for the discovery of novel antibiotic molecules from arthropod venoms.
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Spider venoms: a rich source of acylpolyamines and peptides as new leads for CNS drugs.
TL;DR: Acylpolyamines and peptides from spider venoms represent an interesting source of molecules for the design of novel pharmaceutical drugs and some spider N-type calcium ion channel blockers may be important for the treatment of chronic pain.
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Oxyopinins, Large Amphipathic Peptides Isolated from the Venom of the Wolf Spider Oxyopes kitabensis with Cytolytic Properties and Positive Insecticidal Cooperativity with Spider Neurotoxins
Gerardo Corzo,Elba Villegas,Froylan Gómez-Lagunas,Lourival D. Possani,Belokoneva Os,Terumi Nakajima +5 more
TL;DR: The results suggest that the linear amphipathic peptides in spider venoms and neuropeptides cooperate to capture insects efficiently.
Journal ArticleDOI
Distinct primary structures of the major peptide toxins from the venom of the spider Macrothele gigas that bind to sites 3 and 4 in the sodium channel.
Gerardo Corzo,Nicolas Gilles,Honoo Satake,Elba Villegas,Li Dai,Terumi Nakajima,Joachim Haupt +6 more
TL;DR: Six peptide toxins (Magi 1–6) were isolated from the Hexathelidae spider Macrothele gigas and Magi 5 is the first spider toxin with binding affinity to site 4 of a mammalian sodium channel.
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Improved Protease Stability of the Antimicrobial Peptide Pin2 Substituted with d-Amino Acids
TL;DR: A d-diastereomer of Pandinin 2, d-Pin2, was constructed to observe if it maintained antimicrobial activity in the same range as the parental one, but with the purpose of reducing its hemolytic activity to human erythrocytes and improving its ability to resist proteolytic cleavage.