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Eleanor Pullenayegum
Researcher at McMaster University
Publications - 53
Citations - 3153
Eleanor Pullenayegum is an academic researcher from McMaster University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 16, co-authored 16 publications receiving 2653 citations. Previous affiliations of Eleanor Pullenayegum include St. Joseph's Healthcare Hamilton & University of Cambridge.
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Journal ArticleDOI
Higher vs Lower Positive End-Expiratory Pressure in Patients With Acute Lung Injury and Acute Respiratory Distress Syndrome: Systematic Review and Meta-analysis
Matthias Briel,Maureen O. Meade,Alain Mercat,Roy G. Brower,Daniel Talmor,Stephen D. Walter,Arthur S. Slutsky,Eleanor Pullenayegum,Qi Zhou,Deborah J. Cook,Laurent Brochard,Jean-Christophe Richard,Francois Lamontagne,Francois Lamontagne,Neera Bhatnagar,Thomas E. Stewart,Gordon H. Guyatt +16 more
TL;DR: Evaluating the association of higher vs lower PEEP with patient-important outcomes in adults with acute lung injury or ARDS who are receiving ventilation with low tidal volumes found that higher levels were associated with improved survival among the subgroup of patients with ARDS, but lower levels were not associated withImproved hospital survival.
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The Effect of Oral Antidiabetic Agents on A1C Levels: A systematic review and meta-analysis
TL;DR: The benefit of initiating an OAD agent is most apparent within the first 4 to 6 months, with A1C levels unlikely to fall more than 1.5% on average.
Journal ArticleDOI
A Time Trade-off-derived Value Set of the EQ-5D-5L for Canada.
Feng Xie,Eleanor Pullenayegum,K Gaebel,Nick Bansback,Stirling Bryan,Arto Ohinmaa,Lise Poissant,Jeffrey A. Johnson +7 more
TL;DR: This is the first TTO-based value set of the EQ-5D-5L for Canada and can be used to support the health utility estimation in economic evaluations for reimbursement decision making in Canada.
Journal ArticleDOI
Potentiating Cancer Immunotherapy Using an Oncolytic Virus
Byram W. Bridle,Kyle B Stephenson,Jeanette E. Boudreau,Sandeep T. Koshy,Natasha Kazdhan,Eleanor Pullenayegum,Jérôme Brunellière,Jonathan L. Bramson,Brian D. Lichty,Yonghong Wan +9 more
TL;DR: It is demonstrated that immunization with an adenoviral vaccine before treatment with an oncolytic vesicular stomatitis virus (VSV) expressing the same tumor antigen (Ag) leads to significantly enhanced antitumoral immunity.
Journal ArticleDOI
Long-Term DHEA Replacement in Primary Adrenal Insufficiency: A Randomized, Controlled Trial
Eleanor M. Gurnell,Penelope J. Hunt,Suzanne Curran,Catherine L. Conway,Eleanor Pullenayegum,Felicia A. Huppert,Juliet E. Compston,Joe Herbert,V. Krishna K. Chatterjee +8 more
TL;DR: Although further long-term studies of DHEA therapy, with dosage adjustment, are desirable, the results support some beneficial effects of prolonged D HEA treatment in Addison's disease.