Elena Parmelli

TL;DR: Opinion leaders alone or in combination with other interventions may successfully promote evidence-based practice, but effectiveness varies both within and between studies.

TL;DR: Trastuzumab significantly improves OS and DFS in HER2-positive women with early and locally advanced breast cancer, although it also significantly increases the risk of CHF and LVEF decline.

TL;DR: An overview of systematic reviews that evaluates the impact of financial incentives on healthcare professional behaviour and patient outcomes found that financial incentives may be effective in changing healthcare professional practice.

TL;DR: EtD frameworks for developing recommendations and making decisions about tests lay out the sequential steps in reviewing and assessing the different types of evidence that need to be linked, and describes the EtD criteria based on examples developed with GRADEpro (www.gradepro.org).

TL;DR: This synopsis of the European Breast Guidelines provides recommendations regarding organized screening programs for women aged 40 to 75 years who are at average risk and the addition of hand-held ultrasonography, automated breast ultr Masonography, or magnetic resonance imaging compared with mammography alone.