Elena Volpi

TL;DR: This review summarizes recent findings and highlights recommendations for protein supplementation in critically ill geriatric patients throughout the stages of recovery, specifically focusing on protein dose, its relationship with caloric needs, and delivery modality.

TL;DR: Findings from this clinical trial indicate that posthospitalization interventions in geriatric patients are feasible at both the institution and patient level.

TL;DR: Expression of several amino acid sensing, transport, and mTORC1 regulatory genes in human skeletal muscle are responsive to an increase in amino acid availability, and potential acute disruption of lysosomal function by ingestion of chloroquine interferes with the normal pattern of gene expression following feeding.

TL;DR: Short-term rapamycin administration may only impair protein synthesis in human skeletal muscle when combined with a stimulus such as resistance exercise or increased amino acid availability.

TL;DR: In this article, a combination of essential amino acids (EAA) with low carbohydrate or high carbohydrate could effectively reduce MPB following resistance exercise and improve muscle protein net balance (NB), and the enhanced muscle protein anabolic response detected when EAA+carbohydrate are ingested postresistance exercise is primarily due to an increase in MPS with minor changes in MPB.