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Eli Vlaisavljevich
Researcher at Virginia Tech
Publications - 86
Citations - 1839
Eli Vlaisavljevich is an academic researcher from Virginia Tech. The author has contributed to research in topics: Histotripsy & Medicine. The author has an hindex of 19, co-authored 58 publications receiving 1049 citations. Previous affiliations of Eli Vlaisavljevich include Michigan Technological University & University of Michigan.
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Journal ArticleDOI
Effects of Ultrasound Frequency and Tissue Stiffness on the Histotripsy Intrinsic Threshold for Cavitation
Eli Vlaisavljevich,Kuang-Wei Lin,Adam D. Maxwell,Matthew Warnez,Lauren Mancia,Rahul Singh,Andrew J. Putnam,Brian Fowlkes,Eric Johnsen,Charles A. Cain,Zhen Xu +10 more
TL;DR: The results of this study indicate that the intrinsic threshold to initiate a histotripsy bubble cloud is not significantly affected by tissue stiffness or ultrasound frequency in the hundreds of kilohertz to megahertz range.
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Image-guided non-invasive ultrasound liver ablation using histotripsy: feasibility study in an in vivo porcine model.
Eli Vlaisavljevich,Yohan Kim,Steven P. Allen,Gabe E. Owens,Shawn J. Pelletier,Charles A. Cain,Kimberly Ives,Zhen Xu +7 more
TL;DR: This work demonstrates that histotripsy is capable of noninvasively fractionating liver tissue while preserving critical anatomical structures within the liver and suggests histotRIpsy has potential for the non-invasive ablation of liver tumors.
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Effects of tissue mechanical properties on susceptibility to histotripsy-induced tissue damage
TL;DR: Stronger tissues with higher ultimate stress, higher density, and lower water content were more resistant to histotripsy damage in comparison to weaker tissues, and a self-limiting vessel-sparing treatment strategy was developed in an attempt to preserve major vessels while fractionating the surrounding target tissue.
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For Whom the Bubble Grows: Physical Principles of Bubble Nucleation and Dynamics in Histotripsy Ultrasound Therapy.
TL;DR: In this review, the action of histotripsy-induced bubbles is discussed, sources of bubble nuclei are reviewed, and bubble activity over the course of single and multiple pulses is outlined.
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Histotripsy-induced cavitation cloud initiation thresholds in tissues of different mechanical properties
TL;DR: Test results support the hypothesis that increased tissue stiffness impedes the expansion of initial bubbles, reducing the scattered tensile pressure, and thus requiring higher initial intensities for cloud initiation, and provide a rational basis to tailor acoustic parameters for fractionation of specific tissues.